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JULIETTE LOVE: Hi, Alpha.

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ALPHA: <i>Hello.</i>

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LOVE: Can you
help me write code?

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ALPHA: <i>I was trained</i>
<i>to answer questions,</i>

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<i>but I'm able to learn.</i>

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LOVE: That's very
open-minded of you.

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ALPHA: <i>Thank you. </i>
<i>I'm glad you're happy with me.</i>

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What's this guy doing?

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ALPHA: <i>That's a developer.</i>

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What do you think
he's working on?

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ALPHA:
<i>That's a tough question.</i>

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<i>He might be working</i>
<i>on a new feature,</i>

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<i>a bug fix or something else.</i>

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It's quite possible.

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ALPHA: <i>Yes.</i>

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LOVE: Do you see my backpack?

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ALPHA:
<i>That's a badminton racket.</i>

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It's a squash racket,
but that's pretty close.

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ALPHA:
<i>That's a badminton racket.</i>

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No, but you're not
the first person

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to make that mistake.

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[UPBEAT MUSIC PLAYING]

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NEWSREADER 1:
<i>AI, the technology</i>

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<i>that has been advancing</i>
<i>at breakneck speed.</i>

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NEWSREADER 2: <i>Artificial</i>
<i>intelligence is all the rage.</i>

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NEWSREADER 3: <i>Some are now</i>
<i>raising alarm about...</i>

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NEWSREADER 4:
<i>It is definitely concerning.</i>

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NEWSREADER 5:
<i>This is an AI arms race.</i>

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NEWSREADER 6: <i>We don't know</i>

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<i>how this is all</i>
<i>going to shake out,</i>

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<i>but it's clear</i>
<i>something is happening.</i>

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DEMIS HASSABIS:
<i>I'm kind of restless.</i>

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<i>Trying to build AGI</i>
<i>is the most exciting journey,</i>

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<i>in my opinion, that humans</i>
<i>have ever embarked on.</i>

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<i>If you're really going</i>
<i>to take that seriously,</i>

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<i>there isn't a lot of time.</i>

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<i>Life's very short.</i>

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<i>My whole life goal is to solve</i>

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<i>artificial</i>
<i>general intelligence.</i>

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<i>And on the way,</i>
<i>use AI as the ultimate tool</i>

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<i>to solve all the world's</i>

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<i>most complex</i>
<i>scientific problems.</i>

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<i>I think that's bigger</i>
<i>than the Internet.</i>

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<i>I think that's bigger</i>
<i>than mobile.</i>

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<i>I think it's more like</i>

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<i>the advent</i>
<i>of electricity or fire.</i>

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ANNOUNCER: <i>World leaders</i>

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<i>and artificial</i>
<i>intelligence experts</i>

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<i>are gathering</i>
<i>for the first ever</i>

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<i>global AI safety summit,</i>

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<i>set to look at the risks</i>

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<i>of the fast growing technology</i>
<i>and also...</i>

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HASSABIS: <i>I think</i>
<i>this is a hugely</i>

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<i>critical moment</i>
<i>for all humanity.</i>

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It feels like
we're on the cusp

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of some incredible things
happening.

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NEWSREADER:
<i>Let me take you through</i>

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<i>some of the reactions</i>
<i>in today's papers.</i>

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HASSABIS: <i>AGI is pretty close,</i>
<i>I think.</i>

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<i>There's clearly huge interest</i>
<i>in what it is capable of,</i>

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<i>where it's taking us.</i>

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HASSABIS: <i>This is the moment</i>

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<i>I've been living</i>
<i>my whole life for.</i>

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<i>I've always been fascinated</i>
<i>by the mind.</i>

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<i>So I set my heart</i>
<i>on studying neuroscience</i>

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<i>because I wanted</i>
<i>to get inspiration</i>

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<i>from the brain for AI.</i>

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ELEANOR MAGUIRE:
<i>I remember asking Demis,</i>

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<i>"What's the end game?"</i>

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You know?
So you're going to come here

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and you're going
to study neuroscience

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and you're going to maybe
get a Ph.D. if you work hard.

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And he said,

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<i>"You know, I want</i>
<i>to be able to solve AI.</i>

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<i>"I want to be able</i>
<i>to solve intelligence."</i>

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HASSABIS: <i>The human brain</i>
<i>is the only existent proof</i>

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<i>we have, perhaps</i>
<i>in the entire universe,</i>

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<i>that general intelligence</i>
<i>is possible at all.</i>

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<i>And I thought</i>
<i>someone in this building</i>

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<i>should be interested</i>

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<i>in general intelligence</i>
<i>like I am.</i>

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<i>And then Shane's name</i>
<i>popped up.</i>

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HOST: Our next speaker today
is Shane Legg.

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He's from New Zealand,

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where he trained in math
and classical ballet.

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Are machines actually
becoming more intelligent?

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Some people say yes,
some people say no.

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It's not really clear.

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We know they're getting
a lot faster

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at doing computations.

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But are we actually
going forwards

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in terms
of general intelligence?

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HASSABIS: <i>We were both</i>
<i>obsessed with AGI,</i>

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<i>artificial</i>
<i>general intelligence.</i>

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So today I'm going
to be talking about

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different approaches
to building AGI.

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With my colleague
Demis Hassabis,

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we're looking at ways
to bring in ideas

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from theoretical neuroscience.

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I felt like we were
the keepers of a secret

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that no one else knew.

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<i>Shane and I knew</i>
<i>no one in academia</i>

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<i>would be supportive</i>
<i>of what we were doing.</i>

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AI was almost
an embarrassing word

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to use in academic circles,
right?

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If you said
you were working on AI,

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then you clearly weren't
a serious scientist.

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<i>So I convinced Shane</i>
<i>the right way to do it</i>

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<i>would be to start a company.</i>

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SHANE LEGG: <i>Okay,</i>
<i>we're going to try to do</i>

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<i>artificial</i>
<i>general intelligence.</i>

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It may not even be possible.

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We're not quite sure
how we're going to do it,

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but we have some ideas
or, kind of, approaches.

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Huge amounts of money,
huge amounts of risk,

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lots and lots of compute.

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And if we pull this off,

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it'll be the biggest thing
ever, right?

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That is a very hard thing
for a typical investor

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to put their money on.

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It's almost like
buying a lottery ticket.

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I'm going to be speaking about
the system of neuroscience

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and how it might be used
to help us build AGI.

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HASSABIS:
<i>Finding initial funding</i>

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<i>for this was very hard.</i>

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<i>We're going to solve</i>
<i>all of intelligence.</i>

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<i>You can imagine</i>
<i>some of the looks I got</i>

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<i>when we were</i>
<i>pitching that around.</i>

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So I'm a V.C.
and I look at about

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700 to 1,000 projects a year.

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And I fund
literally 1% of those.

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About eight projects a year.

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So that means 99% of the time,
you're in "No" mode.

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"Wait a minute.
I'm telling you,

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"this is the most important
thing of all time.

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"I'm giving you
all this build-up

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"about how... explain

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"how it connects
with the brain,

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"why the time's right now,
and then you're asking me,

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"'But what's your, how are you
going to make money?

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"'What's your product?'"

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It's like,
so prosaic a question.

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You know?

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"Have you not been listening
to what I've been saying?"

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LEGG: <i>We needed investors</i>

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<i>who aren't necessarily</i>
<i>going to invest</i>

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<i>because they think</i>
<i>it's the best</i>

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<i>investment decision.</i>

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They're probably
going to invest

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because they just think
it's really cool.

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NEWSREADER:
<i>He's the Silicon Valley</i>

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<i>version of the man</i>
<i>behind the curtain</i>

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<i>in</i>The Wizard of Oz.

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<i>He had a lot to do</i>
<i>with giving you</i>

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<i>PayPal, Facebook,</i>
<i>YouTube and Yelp.</i>

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LEGG: <i>If everyone says "X,"</i>

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Peter Thiel suspects
that the opposite of X

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is quite possibly true.

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HASSABIS: <i>So Peter Thiel</i>
<i>was our first big investor.</i>

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But he insisted that
we come to Silicon Valley

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because that
was the only place we could...

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There would be the talent,

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and we could build
that kind of company.

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<i>But I was pretty adamant</i>
<i>we should be in London</i>

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<i>because I think</i>
<i>London's an amazing city.</i>

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<i>Plus, I knew there were</i>
<i>really amazing people</i>

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<i>trained at Cambridge</i>
<i>and Oxford and UCL.</i>

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<i>In Silicon Valley,</i>

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everybody's founding
a company every year,

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and then if it doesn't work,

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you chuck it
and you start something new.

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That is not conducive

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to a long-term
research challenge.

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<i>So we were totally</i>
<i>an outlier for him.</i>

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Hi, everyone.
Welcome to DeepMind.

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So, what is our mission?

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We summarize it as...

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DeepMind's mission is to build
the world's first

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general learning machine.

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So we always stress the word
"general" and "learning" here

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are the key things.

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LEGG: <i>Our mission</i>
<i>was to build an AGI,</i>

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<i>an artificial</i>
<i>general intelligence.</i>

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And so that means that we need
a system which is general.

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It doesn't learn to do
one specific thing.

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<i>That's a really key part</i>
<i>of human intelligence.</i>

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<i>We can learn to do</i>
<i>many, many things.</i>

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It's going to, of course,
be a lot of hard work.

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But one of the things
that keeps me up at night

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is to not waste this
opportunity to, you know,

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to really make
a difference here,

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and have a big impact
on the world.

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LEGG: <i>The first people</i>
<i>that came</i>

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<i>and joined DeepMind</i>
<i>really believed in the dream.</i>

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<i>But this was, I think,</i>
<i>one of the first times</i>

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<i>they found a place</i>
<i>full of other dreamers.</i>

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You know, we collected
this Manhattan Project,

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if you like,
together to solve AI.

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HELEN KING:
<i>In the first two years,</i>

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<i>we were in total stealth mode.</i>

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And so we couldn't
say to anyone

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what were we doing
or where we worked.

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It was all quite vague.

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BEN COPPIN: <i>It had</i>
<i>no public presence at all.</i>

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<i>You couldn't</i>
<i>look at a website.</i>

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<i>The office</i>
<i>was at a secret location.</i>

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When we would interview people
in those early days,

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they would show up
very nervously.

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[LAUGHS]

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I had at least one candidate
who said,

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"I just messaged my wife
to tell her exactly

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"where I'm going just in case

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"this turns out to be some
kind of horrible scam

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"and I'm going
to get kidnapped."

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Well, my favorite new person
who's an investor,

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00:08:39,736 --> 00:08:43,000
who I've been working
for a year, is Elon Musk.

222
00:08:43,044 --> 00:08:44,132
So for those of you
who don't know,

223
00:08:44,175 --> 00:08:45,350
this is what he looks like.

224
00:08:45,394 --> 00:08:47,483
And he hadn't really thought
much about AI

225
00:08:47,527 --> 00:08:49,137
until we chatted.

226
00:08:49,180 --> 00:08:51,269
His mission is to die on Mars
or something.

227
00:08:51,313 --> 00:08:52,923
- But not on impact.
- [LAUGHTER]

228
00:08:52,967 --> 00:08:54,185
So...

229
00:08:55,186 --> 00:08:57,145
<i>We made some big decisions</i>

230
00:08:57,188 --> 00:08:59,321
about how we were going
to approach building AI.

231
00:08:59,364 --> 00:09:01,105
This is a reinforcement
learning setup.

232
00:09:01,149 --> 00:09:02,803
This is the kind of setup
that we think about

233
00:09:02,846 --> 00:09:06,328
when we say we're building,
you know, an AI agent.

234
00:09:06,371 --> 00:09:08,504
It's basically the agent,
which is the AI,

235
00:09:08,548 --> 00:09:09,984
and then there's
the environment

236
00:09:10,027 --> 00:09:11,159
that it's interacting with.

237
00:09:11,202 --> 00:09:12,464
<i>We decided that games,</i>

238
00:09:12,508 --> 00:09:13,988
as long as
you're very disciplined

239
00:09:14,031 --> 00:09:15,293
about how you use them,

240
00:09:15,337 --> 00:09:17,252
are the perfect
training ground

241
00:09:17,295 --> 00:09:19,341
for AI development.

242
00:09:19,384 --> 00:09:21,691
LEGG: <i>We wanted </i>
<i>to try to create one algorithm</i>

243
00:09:21,735 --> 00:09:23,650
<i>that could to be</i>
<i>trained up to play</i>

244
00:09:23,693 --> 00:09:26,043
<i>several dozen</i>
<i>different Atari games.</i>

245
00:09:26,087 --> 00:09:27,479
So just like a human,

246
00:09:27,523 --> 00:09:29,525
you have to use the same brain
to play all the games.

247
00:09:29,569 --> 00:09:30,874
DAVID SILVER:
<i>You can think of it</i>

248
00:09:30,918 --> 00:09:33,007
<i>that you provide the agent</i>
<i>with the cartridge.</i>

249
00:09:33,050 --> 00:09:34,312
<i>And you say,</i>

250
00:09:34,356 --> 00:09:35,705
<i>"Okay, imagine you're born</i>
<i>into that world</i>

251
00:09:35,749 --> 00:09:37,533
"with that cartridge,
and you just get to interact

252
00:09:37,577 --> 00:09:39,404
"with the pixels
and see the score.

253
00:09:40,362 --> 00:09:41,668
"What can you do?"

254
00:09:43,974 --> 00:09:47,369
So what you're going to do is
take your Q function. Q-K...

255
00:09:47,412 --> 00:09:49,197
HASSABIS: <i>Q-learning</i>
<i>is one of the oldest methods</i>

256
00:09:49,240 --> 00:09:50,894
<i>for reinforcement learning.</i>

257
00:09:50,938 --> 00:09:53,680
<i>And what we did was combine</i>
<i>reinforcement learning</i>

258
00:09:53,723 --> 00:09:56,770
<i>with deep learning</i>
<i>in one system.</i>

259
00:09:56,813 --> 00:09:59,337
<i>No one had ever combined</i>
<i>those two things together</i>

260
00:09:59,381 --> 00:10:01,426
<i>at scale to do</i>
<i>anything impressive,</i>

261
00:10:01,470 --> 00:10:03,515
<i>and we needed</i>
<i>to prove out this thesis.</i>

262
00:10:03,559 --> 00:10:06,780
LEGG: <i>We tried doing</i>Pong
<i>as the first game.</i>

263
00:10:06,823 --> 00:10:08,129
<i>It seemed like the simplest.</i>

264
00:10:08,172 --> 00:10:10,218
It hasn't been told

265
00:10:10,261 --> 00:10:11,828
anything about
what it's controlling

266
00:10:11,872 --> 00:10:12,873
or what it's supposed to do.

267
00:10:12,916 --> 00:10:14,657
All it knows
is that score is good

268
00:10:14,701 --> 00:10:18,052
and it has to learn
what its controls do,

269
00:10:18,095 --> 00:10:20,620
and build everything...
first principles.

270
00:10:21,229 --> 00:10:22,752
[GAME BEEPING]

271
00:10:29,193 --> 00:10:30,412
It wasn't really working.

272
00:10:32,588 --> 00:10:34,068
HASSABIS: <i>I was just</i>
<i>saying to Shane,</i>

273
00:10:34,111 --> 00:10:37,071
<i>"Maybe we're just wrong,</i>
<i>and we can't even do</i>Pong."

274
00:10:37,114 --> 00:10:38,812
LEGG: <i>It was a bit</i>
<i>nerve-racking,</i>

275
00:10:38,855 --> 00:10:40,422
thinking how far we had to go

276
00:10:40,465 --> 00:10:42,337
if we were going
to really build

277
00:10:42,380 --> 00:10:44,426
a generally
intelligent system.

278
00:10:44,469 --> 00:10:45,732
HASSABIS: <i>And it felt like</i>
<i>it was time</i>

279
00:10:45,775 --> 00:10:47,255
<i>to give up and move on.</i>

280
00:10:48,169 --> 00:10:49,387
<i>And then suddenly...</i>

281
00:10:49,431 --> 00:10:51,346
[STIRRING MUSIC PLAYS]

282
00:10:51,389 --> 00:10:53,609
<i>We got our first point.</i>

283
00:10:53,653 --> 00:10:56,612
<i>And then it was like,</i>
<i>"Is this random?"</i>

284
00:10:56,656 --> 00:10:59,180
<i>"No, no, it's really</i>
<i>getting a point now."</i>

285
00:10:59,223 --> 00:11:00,703
It was really exciting
that this thing

286
00:11:00,747 --> 00:11:02,226
that previously
couldn't even figure out

287
00:11:02,270 --> 00:11:03,532
how to move a paddle

288
00:11:03,575 --> 00:11:05,926
had suddenly been able
to totally get it right.

289
00:11:05,969 --> 00:11:07,144
HASSABIS: <i>Then it was getting</i>
<i>a few points.</i>

290
00:11:07,188 --> 00:11:08,624
<i>And then it won</i>
<i>its first game.</i>

291
00:11:08,668 --> 00:11:10,974
<i>And then three months later,</i>
<i>no human could beat it.</i>

292
00:11:11,018 --> 00:11:14,238
<i>You hadn't told it the rules, </i>
<i>how to get the score, nothing.</i>

293
00:11:14,282 --> 00:11:16,110
<i>And you just tell it</i>
<i>to maximize the score,</i>

294
00:11:16,153 --> 00:11:17,372
<i>and it goes away and does it.</i>

295
00:11:17,415 --> 00:11:18,678
<i>This is the first time</i>

296
00:11:18,721 --> 00:11:20,549
<i>anyone had done</i>
<i>this end-to-end learning.</i>

297
00:11:20,592 --> 00:11:24,292
"Okay, so we have this working
in quite a general way.

298
00:11:24,335 --> 00:11:25,772
<i>"Now let's try another game."</i>

299
00:11:25,815 --> 00:11:27,512
HASSABIS: <i>So then</i>
<i>we tried</i>Breakout.

300
00:11:27,556 --> 00:11:29,123
At the beginning,
after 100 games,

301
00:11:29,166 --> 00:11:30,777
the agent is not very good.

302
00:11:30,820 --> 00:11:32,474
It's missing the ball
most of the time,

303
00:11:32,517 --> 00:11:34,389
but it's starting to get
the hang of the idea

304
00:11:34,432 --> 00:11:35,999
that the bat should go
towards the ball.

305
00:11:36,043 --> 00:11:37,566
<i>Now, after 300 games,</i>

306
00:11:37,609 --> 00:11:40,656
<i>it's about as good as</i>
<i>any human can play this.</i>

307
00:11:40,700 --> 00:11:42,049
We thought,
"Well, that's pretty cool,"

308
00:11:42,092 --> 00:11:44,312
but we left the system playing
for another 200 games,

309
00:11:44,355 --> 00:11:46,053
and it did this amazing thing.

310
00:11:46,096 --> 00:11:47,358
It found the optimal strategy

311
00:11:47,402 --> 00:11:49,404
was to dig a tunnel
around the side

312
00:11:49,447 --> 00:11:51,667
and put the ball
around the back of the wall.

313
00:11:51,711 --> 00:11:53,234
KORAY KAVUKCUOGLU:
<i>Finally, the agent</i>

314
00:11:53,277 --> 00:11:54,365
<i>is actually achieving</i>

315
00:11:54,409 --> 00:11:55,627
<i>what you thought</i>
<i>it would achieve.</i>

316
00:11:55,671 --> 00:11:57,325
That is a great feeling.
Right?

317
00:11:57,368 --> 00:11:59,283
Like, I mean,
when we do research,

318
00:11:59,327 --> 00:12:00,676
that is the best
we can hope for.

319
00:12:00,720 --> 00:12:03,200
<i>We started generalizing</i>
<i>to 50 games,</i>

320
00:12:03,244 --> 00:12:05,463
<i>and we basically</i>
<i>created a recipe.</i>

321
00:12:05,507 --> 00:12:06,813
<i>We could just take a game</i>

322
00:12:06,856 --> 00:12:08,379
<i>that we have</i>
<i>never seen before.</i>

323
00:12:08,423 --> 00:12:09,903
<i>We would run</i>
<i>the algorithm on that,</i>

324
00:12:09,946 --> 00:12:13,036
<i>and DQN could train itself</i>
<i>from scratch,</i>

325
00:12:13,080 --> 00:12:14,429
<i>achieving human level</i>

326
00:12:14,472 --> 00:12:15,996
<i>or sometimes better</i>
<i>than human level.</i>

327
00:12:16,039 --> 00:12:18,433
LEGG: <i>We didn't build it</i>
<i>to play any of them.</i>

328
00:12:18,476 --> 00:12:20,522
We could just give it
a bunch of games

329
00:12:20,565 --> 00:12:22,654
and would figure it out
for itself.

330
00:12:22,698 --> 00:12:25,179
And there was something
quite magical in that.

331
00:12:25,222 --> 00:12:26,528
MURRAY SHANAHAN:
<i>Suddenly you had something</i>

332
00:12:26,571 --> 00:12:27,921
<i>that would respond and learn</i>

333
00:12:27,964 --> 00:12:30,358
<i>whatever situation</i>
<i>it was parachuted into.</i>

334
00:12:30,401 --> 00:12:33,013
<i>And that was like a huge,</i>
<i>huge breakthrough.</i>

335
00:12:33,056 --> 00:12:35,276
<i>It was in many respects</i>

336
00:12:35,319 --> 00:12:36,625
the first example

337
00:12:36,668 --> 00:12:39,062
of any kind of thing
you could call

338
00:12:39,106 --> 00:12:40,542
a general intelligence.

339
00:12:42,109 --> 00:12:43,893
HASSABIS: <i>Although we were</i>
<i>a well-funded startup,</i>

340
00:12:43,937 --> 00:12:47,375
<i>holding us back</i>
<i>was not enough compute power.</i>

341
00:12:47,418 --> 00:12:49,203
<i>I realized that</i>
<i>this would accelerate</i>

342
00:12:49,246 --> 00:12:51,466
<i>our time scale</i>
<i>to AGI massively.</i>

343
00:12:51,509 --> 00:12:53,163
I used to see Demis
quite frequently.

344
00:12:53,207 --> 00:12:55,035
We'd have lunch, and he did...

345
00:12:56,210 --> 00:12:58,865
say to me that
he had two companies

346
00:12:58,908 --> 00:13:02,564
that were involved
in buying DeepMind.

347
00:13:02,607 --> 00:13:04,609
And he didn't know
which one to go with.

348
00:13:04,653 --> 00:13:08,526
<i>The issue was,</i>
<i>would any commercial company</i>

349
00:13:08,570 --> 00:13:12,661
<i>appreciate the real importance</i>
<i>of the research?</i>

350
00:13:12,704 --> 00:13:15,838
And give the research time
to come to fruition

351
00:13:15,882 --> 00:13:17,797
and not be breathing down
their necks,

352
00:13:17,840 --> 00:13:21,539
<i>saying, "We want some kind of </i>
<i>commercial benefit from this."</i>

353
00:13:23,411 --> 00:13:24,586
[MACHINERY HUMMING]

354
00:13:27,284 --> 00:13:32,463
Google has bought DeepMind
for a reported £400,000,000,

355
00:13:32,507 --> 00:13:34,726
making the artificial
intelligence firm

356
00:13:34,770 --> 00:13:37,947
its largest
European acquisition so far.

357
00:13:37,991 --> 00:13:39,644
<i>The company was founded</i>

358
00:13:39,688 --> 00:13:43,344
<i>by 37-year-old entrepreneur</i>
<i>Demis Hassabis.</i>

359
00:13:43,387 --> 00:13:45,563
After the acquisition,
I started mentoring

360
00:13:45,607 --> 00:13:47,261
and spending time with Demis,

361
00:13:47,304 --> 00:13:48,915
and just listening to him.

362
00:13:48,958 --> 00:13:52,396
And this is a person
who fundamentally

363
00:13:52,440 --> 00:13:55,573
is a scientist
and a natural scientist.

364
00:13:55,617 --> 00:13:58,489
He wants science to solve
every problem in the world,

365
00:13:58,533 --> 00:14:00,622
and he believes it can do so.

366
00:14:00,665 --> 00:14:03,625
That's not a normal person
you find in a tech company.

367
00:14:05,496 --> 00:14:07,455
HASSABIS: We were able
to not only join Google

368
00:14:07,498 --> 00:14:10,240
but run independently
in London,

369
00:14:10,284 --> 00:14:11,328
build our culture,

370
00:14:11,372 --> 00:14:13,461
which was optimized
for breakthroughs

371
00:14:13,504 --> 00:14:15,419
and not deal with products,

372
00:14:15,463 --> 00:14:17,726
do pure research.

373
00:14:17,769 --> 00:14:19,293
<i>Our investors</i>
<i>didn't want to sell,</i>

374
00:14:19,336 --> 00:14:20,685
<i>but we decided</i>

375
00:14:20,729 --> 00:14:22,731
<i>that this was the best thing</i>
<i>for the mission.</i>

376
00:14:22,774 --> 00:14:24,646
<i>In many senses,</i>
<i>we were underselling</i>

377
00:14:24,689 --> 00:14:26,169
<i>in terms of value</i>
<i>before it more matured,</i>

378
00:14:26,213 --> 00:14:28,128
<i>and you could have sold it</i>
<i>for a lot more money.</i>

379
00:14:28,171 --> 00:14:32,828
<i>And the reason is because</i>
<i>there's no time to waste.</i>

380
00:14:32,872 --> 00:14:35,178
There's so many things
that got to be cracked

381
00:14:35,222 --> 00:14:37,659
while the brain
is still in gear.

382
00:14:37,702 --> 00:14:39,008
You know, I'm still alive.

383
00:14:39,052 --> 00:14:40,880
There's all these things
that gotta be done.

384
00:14:40,923 --> 00:14:42,925
So you haven't got--
I mean, how many...

385
00:14:42,969 --> 00:14:44,492
How many billions
would you trade for

386
00:14:44,535 --> 00:14:45,797
another five years of life,
you know,

387
00:14:45,841 --> 00:14:48,365
to do what you set out to do?

388
00:14:48,409 --> 00:14:49,758
Okay, all of a sudden,

389
00:14:49,801 --> 00:14:52,717
we've got this massive scale
compute available to us.

390
00:14:52,761 --> 00:14:53,936
What can we do with that?

391
00:14:56,591 --> 00:14:59,942
HASSABIS: <i>Go is the pinnacle</i>
<i>of board games.</i>

392
00:14:59,986 --> 00:15:04,642
<i>It is the most complex game</i>
<i>ever devised by man.</i>

393
00:15:04,686 --> 00:15:06,688
<i>There are more possible</i>
<i>board configurations</i>

394
00:15:06,731 --> 00:15:09,821
<i>in the game of Go than there</i>
<i>are atoms in the universe.</i>

395
00:15:09,865 --> 00:15:13,390
SILVER: <i>Go is the holy grail</i>
<i>of artificial intelligence.</i>

396
00:15:13,434 --> 00:15:14,522
<i>For many years,</i>

397
00:15:14,565 --> 00:15:16,002
<i>people have looked</i>
<i>at this game</i>

398
00:15:16,045 --> 00:15:17,917
<i>and they've thought,</i>
<i>"Wow, this is just too hard."</i>

399
00:15:17,960 --> 00:15:20,180
Everything we've ever
tried in AI,

400
00:15:20,223 --> 00:15:22,704
it just falls over when
you try the game of Go.

401
00:15:22,747 --> 00:15:23,966
<i>And so that's why</i>
<i>it feels like</i>

402
00:15:24,010 --> 00:15:26,099
<i>a real litmus test</i>
<i>of progress.</i>

403
00:15:26,142 --> 00:15:28,579
We had just bought DeepMind.

404
00:15:28,623 --> 00:15:30,712
They were working
on reinforcement learning

405
00:15:30,755 --> 00:15:32,975
<i>and they were the world's</i>
<i>experts in games.</i>

406
00:15:33,019 --> 00:15:34,846
<i>And so when</i>
<i>they introduced the idea</i>

407
00:15:34,890 --> 00:15:37,197
<i>that they could beat</i>
<i>the top level Go players</i>

408
00:15:37,240 --> 00:15:40,113
<i>in a game that was thought</i>
<i>to be incomputable,</i>

409
00:15:40,156 --> 00:15:42,724
I thought, "Well,
that's pretty interesting."

410
00:15:42,767 --> 00:15:46,467
Our ultimate next step
is to play the legendary

411
00:15:46,510 --> 00:15:49,209
Lee Sedol
in just over two weeks.

412
00:15:50,514 --> 00:15:52,038
NEWSREADER 1:
<i>A match like no other</i>

413
00:15:52,081 --> 00:15:54,257
<i>is about to get underway</i>
<i>in South Korea.</i>

414
00:15:54,301 --> 00:15:57,826
NEWSREADER 2: <i>Lee Sedol</i>
<i>is getting ready to rumble.</i>

415
00:15:57,869 --> 00:15:59,262
HASSABIS:
<i>Lee Sedol is probably</i>

416
00:15:59,306 --> 00:16:01,699
<i>one of the greatest players</i>
<i>of the last decade.</i>

417
00:16:01,743 --> 00:16:04,224
<i>I describe him</i>
<i>as the Roger Federer of Go.</i>

418
00:16:05,573 --> 00:16:06,922
ERIC SCHMIDT: <i>He showed up,</i>

419
00:16:06,966 --> 00:16:09,838
<i>and all of a sudden</i>
<i>we have a thousand Koreans</i>

420
00:16:09,881 --> 00:16:13,059
who represent
all of Korean society,

421
00:16:13,102 --> 00:16:14,190
the top Go players.

422
00:16:15,583 --> 00:16:17,802
<i>And then we have Demis.</i>

423
00:16:17,846 --> 00:16:19,848
<i>And the great</i>
<i>engineering team.</i>

424
00:16:20,588 --> 00:16:22,285
He's very famous

425
00:16:22,329 --> 00:16:25,506
for very creative
fighting play.

426
00:16:25,549 --> 00:16:28,770
<i>So this could be</i>
<i>difficult for us.</i>

427
00:16:28,813 --> 00:16:31,991
SCHMIDT: <i>I figured Lee Sedol</i>
<i>is going to beat these guys,</i>

428
00:16:32,034 --> 00:16:34,297
<i>but they'll make</i>
<i>a good showing.</i>

429
00:16:34,341 --> 00:16:35,733
Good for a startup.

430
00:16:38,040 --> 00:16:39,563
<i>I went over</i>
<i>to the technical group</i>

431
00:16:39,607 --> 00:16:40,912
<i>and they said,</i>

432
00:16:40,956 --> 00:16:42,305
<i>"Let me show you</i>
<i>how our algorithm works."</i>

433
00:16:43,654 --> 00:16:45,091
RESEARCHER: If you step
through the actual game,

434
00:16:45,134 --> 00:16:47,789
we can see, kind of,
how AlphaGo thinks.

435
00:16:47,832 --> 00:16:50,226
HASSABIS: <i>The way we start off</i>
<i>on training AlphaGo</i>

436
00:16:50,270 --> 00:16:52,968
<i>is by showing it 100,000 games</i>

437
00:16:53,012 --> 00:16:54,491
<i>that strong amateurs</i>
<i>have played.</i>

438
00:16:54,535 --> 00:16:55,710
<i>And we first initially</i>

439
00:16:55,753 --> 00:16:58,887
<i>get AlphaGo to mimic</i>
<i>the human player,</i>

440
00:16:58,930 --> 00:17:00,802
<i>and then through</i>
<i>reinforcement learning,</i>

441
00:17:00,845 --> 00:17:02,369
<i>it plays against</i>
<i>different versions of itself</i>

442
00:17:02,412 --> 00:17:05,720
<i>many millions of times</i>
<i>and learns from its errors.</i>

443
00:17:05,763 --> 00:17:07,591
Hmm, this is interesting.

444
00:17:07,635 --> 00:17:08,679
ANNOUNCER 1: All right, folks,

445
00:17:08,723 --> 00:17:10,594
you're going to see
history made.

446
00:17:10,638 --> 00:17:11,856
[ANNOUNCER 2 SPEAKING KOREAN]

447
00:17:12,770 --> 00:17:14,772
SCHMIDT: <i>So the game starts.</i>

448
00:17:14,816 --> 00:17:15,991
ANNOUNCER 1:
<i>He's really concentrating.</i>

449
00:17:16,035 --> 00:17:17,645
ANNOUNCER 3:
<i>If you really look at the...</i>

450
00:17:19,473 --> 00:17:20,865
[ANNOUNCERS EXCLAIM]

451
00:17:20,909 --> 00:17:25,348
That's a very surprising move.

452
00:17:25,392 --> 00:17:27,916
ANNOUNCER 3: I think we're
seeing an original move here.

453
00:17:34,401 --> 00:17:35,793
Yeah, that's an exciting move.

454
00:17:36,185 --> 00:17:37,230
I like...

455
00:17:37,273 --> 00:17:38,579
SILVER:
<i>Professional commentators</i>

456
00:17:38,622 --> 00:17:40,102
<i>almost unanimously said</i>

457
00:17:40,146 --> 00:17:43,323
<i>that not a single human player</i>
<i>would have chosen move 37.</i>

458
00:17:43,366 --> 00:17:45,803
<i>So I actually had a poke</i>
<i>around in AlphaGo</i>

459
00:17:45,847 --> 00:17:47,414
<i>to see what AlphaGo thought.</i>

460
00:17:47,457 --> 00:17:50,330
<i>And AlphaGo actually agreed</i>
<i>with that assessment.</i>

461
00:17:50,373 --> 00:17:53,811
<i>AlphaGo said there was a one</i>
<i>in 10,000 probability</i>

462
00:17:53,855 --> 00:17:57,772
<i>that move 37 would have been</i>
<i>played by a human player.</i>

463
00:17:57,815 --> 00:18:00,775
[SEDOL SPEAKING IN KOREAN]

464
00:18:08,826 --> 00:18:10,176
SILVER: <i>The game of Go</i>
<i>has been studied</i>

465
00:18:10,219 --> 00:18:11,568
<i>for thousands of years.</i>

466
00:18:11,612 --> 00:18:15,137
<i>And AlphaGo discovered</i>
<i>something completely new.</i>

467
00:18:16,878 --> 00:18:19,707
ANNOUNCER: He resigned.
Lee Sedol has just resigned.

468
00:18:19,750 --> 00:18:21,187
He's beaten.

469
00:18:21,230 --> 00:18:22,666
[ELECTRONIC MUSIC PLAYING]

470
00:18:22,710 --> 00:18:24,668
NEWSREADER 1: <i>The battle</i>
<i>between man versus machine,</i>

471
00:18:24,712 --> 00:18:26,235
<i>a computer just came out</i>
<i>the victor.</i>

472
00:18:26,279 --> 00:18:28,237
NEWSREADER 2: <i>Google</i>
<i>put its DeepMind team</i>

473
00:18:28,281 --> 00:18:29,673
<i>to the test against</i>

474
00:18:29,717 --> 00:18:32,023
<i>one of the brightest minds</i>
<i>in the world and won.</i>

475
00:18:32,067 --> 00:18:33,721
SCHMIDT:
<i>That's when we realized</i>

476
00:18:33,764 --> 00:18:35,244
<i>the DeepMind people knew</i>
<i>what they were doing</i>

477
00:18:35,288 --> 00:18:37,551
<i>and to pay attention</i>
<i>to reinforcement learning</i>

478
00:18:37,594 --> 00:18:38,900
<i>as they have invented it.</i>

479
00:18:40,075 --> 00:18:41,816
<i>Based on that experience,</i>

480
00:18:41,859 --> 00:18:44,819
<i>AlphaGo got better</i>
<i>and better and better.</i>

481
00:18:44,862 --> 00:18:45,950
And they had a little chart

482
00:18:45,994 --> 00:18:47,517
of how much better
they were getting.

483
00:18:47,561 --> 00:18:49,302
And I said,
"When does this stop?"

484
00:18:50,085 --> 00:18:50,999
And Demis said,

485
00:18:51,042 --> 00:18:52,696
"When we beat the Chinese guy,

486
00:18:52,740 --> 00:18:55,743
<i>"the top-rated player</i>
<i>in the world."</i>

487
00:18:56,961 --> 00:18:59,225
ANNOUNCER 1:
<i>Ke Jie versus AlphaGo.</i>

488
00:19:03,620 --> 00:19:04,795
ANNOUNCER 2:
And I think we will see

489
00:19:04,839 --> 00:19:06,145
AlphaGo pushing through there.

490
00:19:06,188 --> 00:19:08,190
ANNOUNCER 1:
AlphaGo is ahead quite a bit.

491
00:19:08,234 --> 00:19:11,454
SCHMIDT: <i>About halfway</i>
<i>through the first game,</i>

492
00:19:11,498 --> 00:19:14,675
<i>the best player in the world</i>
<i>was not doing so well.</i>

493
00:19:14,718 --> 00:19:17,808
ANNOUNCER 1:
What can black do here?

494
00:19:19,114 --> 00:19:21,247
ANNOUNCER 2: Looks difficult.

495
00:19:21,290 --> 00:19:23,336
SCHMIDT:
<i>And at a critical moment...</i>

496
00:19:32,997 --> 00:19:35,913
the Chinese government
ordered the feed cut off.

497
00:19:38,307 --> 00:19:41,745
<i>It was at that moment</i>
<i>we were telling the world</i>

498
00:19:41,789 --> 00:19:44,966
<i>that something new</i>
<i>had arrived on earth.</i>

499
00:19:47,621 --> 00:19:48,970
<i>In the 1950s</i>

500
00:19:49,013 --> 00:19:51,929
<i>when Russia's</i>Sputnik
<i>satellite was launched,</i>

501
00:19:53,279 --> 00:19:55,194
<i>it changed</i>
<i>the course of history.</i>

502
00:19:55,237 --> 00:19:57,544
TV HOST: <i>It is a challenge</i>
<i>that America must meet</i>

503
00:19:57,587 --> 00:19:59,633
<i>to survive in the Space Age.</i>

504
00:19:59,676 --> 00:20:02,375
SCHMIDT: <i>This has been</i>
<i>called the</i>Sputnik <i>moment.</i>

505
00:20:02,418 --> 00:20:06,335
The <i>Sputnik</i>moment created
a massive reaction in the US

506
00:20:06,379 --> 00:20:10,034
<i>in terms of funding</i>
<i>for science and engineering,</i>

507
00:20:10,078 --> 00:20:12,254
<i>and particularly</i>
<i>of space technology.</i>

508
00:20:12,298 --> 00:20:15,823
For China,
AlphaGo was the wakeup call,

509
00:20:15,866 --> 00:20:17,128
the <i>Sputnik</i>moment.

510
00:20:17,172 --> 00:20:19,870
<i>It launched an AI space race.</i>

511
00:20:21,220 --> 00:20:23,047
HASSABIS: <i>We had this</i>
<i>huge idea that worked,</i>

512
00:20:23,091 --> 00:20:26,355
<i>and now the whole world knows.</i>

513
00:20:26,399 --> 00:20:28,879
<i>It's always easier</i>
<i>to land on the moon</i>

514
00:20:28,923 --> 00:20:30,838
<i>if someone's already</i>
<i>landed there.</i>

515
00:20:32,056 --> 00:20:34,450
<i>It is going to matter</i>
<i>who builds AI,</i>

516
00:20:34,494 --> 00:20:36,626
<i>and how it gets built.</i>

517
00:20:36,670 --> 00:20:38,324
<i>I always feel that pressure.</i>

518
00:20:42,066 --> 00:20:43,764
SILVER: <i>There's been</i>
<i>a big chain of events</i>

519
00:20:43,807 --> 00:20:46,680
<i>that followed on from all</i>
<i>of the excitement of AlphaGo.</i>

520
00:20:46,723 --> 00:20:48,072
<i>When we played</i>
<i>against Lee Sedol,</i>

521
00:20:48,116 --> 00:20:49,248
<i>we actually had a system</i>

522
00:20:49,291 --> 00:20:50,684
<i>that had been trained</i>
<i>on human data,</i>

523
00:20:50,727 --> 00:20:52,251
<i>on all of the millions</i>
<i>of games</i>

524
00:20:52,294 --> 00:20:55,036
<i>that have been played</i>
<i>by human experts.</i>

525
00:20:55,079 --> 00:20:56,994
<i>We eventually found</i>
<i>a new algorithm,</i>

526
00:20:57,038 --> 00:20:59,170
<i>a much more elegant approach</i>
<i>to the whole system,</i>

527
00:20:59,214 --> 00:21:01,172
which actually stripped out
all of the human knowledge

528
00:21:01,216 --> 00:21:03,697
and just started
completely from scratch.

529
00:21:03,740 --> 00:21:06,700
<i>And that became a project</i>
<i>which we called AlphaZero.</i>

530
00:21:06,743 --> 00:21:09,529
<i>Zero, meaning having zero</i>
<i>human knowledge in the loop.</i>

531
00:21:11,879 --> 00:21:13,054
<i>Instead of learning</i>
<i>from human data,</i>

532
00:21:13,097 --> 00:21:15,796
<i>it learned from its own games.</i>

533
00:21:15,839 --> 00:21:17,841
<i>So it actually</i>
<i>became its own teacher.</i>

534
00:21:21,280 --> 00:21:23,499
HASSABIS:
<i>AlphaZero is an experiment</i>

535
00:21:23,543 --> 00:21:26,720
<i>in how little knowledge</i>
<i>can we put into these systems</i>

536
00:21:26,763 --> 00:21:28,243
<i>and how quickly</i>
<i>and how efficiently</i>

537
00:21:28,287 --> 00:21:29,723
<i>can they learn?</i>

538
00:21:29,766 --> 00:21:32,552
<i>But the other thing is AlphaZero</i>
<i>doesn't have any rules.</i>

539
00:21:32,595 --> 00:21:33,553
<i>It learns through experience.</i>

540
00:21:36,120 --> 00:21:38,862
<i>The next stage</i>
<i>was to make it more general,</i>

541
00:21:38,906 --> 00:21:40,995
<i>so that it could play</i>
<i>any two-player game.</i>

542
00:21:41,038 --> 00:21:42,344
<i>Things like chess,</i>

543
00:21:42,388 --> 00:21:44,085
<i>and in fact,</i>
<i>any kind of two-player</i>

544
00:21:44,128 --> 00:21:45,391
<i>perfect information game.</i>

545
00:21:45,434 --> 00:21:46,653
It's going really well.

546
00:21:46,696 --> 00:21:47,828
It's going
really, really well.

547
00:21:47,871 --> 00:21:50,091
- Oh, wow.
- It's going down, like fast.

548
00:21:50,134 --> 00:21:53,050
HASSABIS: <i>AlphaGo used </i>
<i>to take a few months to train,</i>

549
00:21:53,094 --> 00:21:55,662
<i>but AlphaZero could start</i>
<i>in the morning</i>

550
00:21:55,705 --> 00:21:57,794
<i>playing completely randomly</i>

551
00:21:57,838 --> 00:22:01,015
<i>and then by tea</i>
<i>be at superhuman level.</i>

552
00:22:01,058 --> 00:22:03,365
<i>And by dinner it will be</i>
<i>the strongest chess entity</i>

553
00:22:03,409 --> 00:22:04,758
<i>there's ever been.</i>

554
00:22:04,801 --> 00:22:06,629
- Amazing, it's amazing.
- Yeah.

555
00:22:06,673 --> 00:22:09,371
It's discovered its own
attacking style, you know,

556
00:22:09,415 --> 00:22:11,417
to take on the current
level of defense.

557
00:22:11,460 --> 00:22:12,766
I mean, I never
in my wildest dreams...

558
00:22:12,809 --> 00:22:14,942
I agree. Actually, I was not
expecting that either.

559
00:22:14,985 --> 00:22:16,422
And it's fun for me.

560
00:22:16,465 --> 00:22:18,598
I mean, it's inspired me
to get back into chess again,

561
00:22:18,641 --> 00:22:20,164
because it's cool to see

562
00:22:20,208 --> 00:22:22,384
<i>that there's even more depth</i>
<i>than we thought in chess.</i>

563
00:22:24,473 --> 00:22:25,431
[HORN BLOWS]

564
00:22:31,611 --> 00:22:34,440
HASSABIS: <i>I actually got</i>
<i>into AI through games.</i>

565
00:22:35,658 --> 00:22:37,660
<i>Initially, it was board games.</i>

566
00:22:37,704 --> 00:22:40,054
<i>I was thinking,</i>
<i>"How is my brain doing this?"</i>

567
00:22:40,097 --> 00:22:41,969
<i>Like, what is it doing?</i>

568
00:22:43,362 --> 00:22:47,148
<i>I was very aware of that</i>
<i>from a very young age.</i>

569
00:22:47,191 --> 00:22:50,064
<i>So I've always been thinking</i>
<i>about thinking.</i>

570
00:22:50,107 --> 00:22:52,762
NEWSREADER: <i>The British</i>
<i>and American chess champions</i>

571
00:22:52,806 --> 00:22:55,025
<i>meet to begin</i>
<i>a series of matches.</i>

572
00:22:55,069 --> 00:22:56,592
<i>Playing alongside them</i>
<i>are the cream</i>

573
00:22:56,636 --> 00:22:59,073
<i>of Britain and America's</i>
<i>youngest players.</i>

574
00:22:59,116 --> 00:23:01,467
NEWSREADER 2: <i>Demis Hassabis</i>
<i>is representing Britain.</i>

575
00:23:06,210 --> 00:23:07,864
COSTAS HASSABIS:
<i>When Demis was four,</i>

576
00:23:07,908 --> 00:23:11,259
he first showed
an aptitude for chess.

577
00:23:12,739 --> 00:23:14,044
<i>By the time he was six,</i>

578
00:23:14,088 --> 00:23:18,048
<i>he became London</i>
<i>under-eight champion.</i>

579
00:23:18,092 --> 00:23:19,485
HASSABIS: <i>My parents</i>
<i>were very interesting</i>

580
00:23:19,528 --> 00:23:20,834
<i>and unusual, actually.</i>

581
00:23:20,877 --> 00:23:23,750
<i>I'd probably describe them</i>
<i>as quite bohemian.</i>

582
00:23:23,793 --> 00:23:25,491
<i>My father</i>
<i>was a singer-songwriter</i>

583
00:23:25,534 --> 00:23:26,709
<i>when he was younger,</i>

584
00:23:26,753 --> 00:23:28,363
<i>and Bob Dylan was his hero.</i>

585
00:23:32,846 --> 00:23:34,500
[HORN HONKS]

586
00:23:34,543 --> 00:23:36,110
[ANGELA HASSABIS SPEAKING]

587
00:23:38,068 --> 00:23:39,287
Yeah, yeah.

588
00:23:41,637 --> 00:23:44,031
HOST: What is it
that you like about this game?

589
00:23:45,075 --> 00:23:47,121
It's just a good
thinking game.

590
00:23:49,253 --> 00:23:51,038
HASSABIS: <i>At the time, </i>
<i>I was the second-highest rated</i>

591
00:23:51,081 --> 00:23:52,692
<i>chess player in the world</i>
<i>for my age.</i>

592
00:23:52,735 --> 00:23:54,345
<i>But although I was on track</i>

593
00:23:54,389 --> 00:23:55,956
<i>to be a professional</i>
<i>chess player,</i>

594
00:23:55,999 --> 00:23:57,523
<i>I thought that was what</i>
<i>I was going to do.</i>

595
00:23:57,566 --> 00:23:59,220
<i>No matter how much</i>
<i>I loved the game,</i>

596
00:23:59,263 --> 00:24:01,222
<i>it was incredibly stressful.</i>

597
00:24:01,265 --> 00:24:03,354
<i>Definitely was not fun</i>
<i>and games for me.</i>

598
00:24:03,398 --> 00:24:05,226
My parents used to, you know,

599
00:24:05,269 --> 00:24:06,923
get very upset
when I lost the game

600
00:24:06,967 --> 00:24:10,405
and angry
if I forgot something.

601
00:24:10,449 --> 00:24:12,407
And because it was quite high
stakes for them, you know,

602
00:24:12,451 --> 00:24:14,061
it cost a lot of money
to go to these tournaments.

603
00:24:14,104 --> 00:24:15,715
And my parents
didn't have much money.

604
00:24:18,413 --> 00:24:19,719
<i>My parents thought, you know,</i>

605
00:24:19,762 --> 00:24:22,069
<i>"If you interested </i>
<i>in being a chess professional,</i>

606
00:24:22,112 --> 00:24:25,376
<i>"this is really important.</i>
<i>It's like your exams."</i>

607
00:24:27,291 --> 00:24:30,077
<i>I remember</i>
<i>I was about 12-years-old</i>

608
00:24:30,120 --> 00:24:32,079
<i>and I was at this </i>
<i>international chess tournament</i>

609
00:24:32,122 --> 00:24:34,255
<i>in Liechtenstein</i>
<i>up in the mountains.</i>

610
00:24:36,562 --> 00:24:39,303
[BELL TOLLING]

611
00:24:43,307 --> 00:24:45,571
<i>And we were in this</i>
<i>huge church hall</i>

612
00:24:47,181 --> 00:24:48,399
<i>with, you know,</i>

613
00:24:48,443 --> 00:24:50,184
<i>hundreds of international</i>
<i>chess players.</i>

614
00:24:52,403 --> 00:24:56,016
<i>And I was playing</i>
<i>the ex-Danish champion.</i>

615
00:24:56,059 --> 00:24:58,801
<i>He must have been</i>
<i>in his 30s, probably.</i>

616
00:25:00,411 --> 00:25:02,979
<i>In those days,</i>
<i>there was a long time limit.</i>

617
00:25:03,023 --> 00:25:05,068
<i>The games could</i>
<i>literally last all day.</i>

618
00:25:05,591 --> 00:25:08,289
[YAWNS]

619
00:25:08,332 --> 00:25:10,813
- [TIMER TICKING]
<i>- We were into our tenth hour.</i>

620
00:25:10,857 --> 00:25:12,380
[TIMER TICKS FRANTICALLY]

621
00:25:17,690 --> 00:25:20,214
[MOUSE GASPS]

622
00:25:20,257 --> 00:25:23,086
<i>And we were in this</i>
<i>incredibly unusual ending.</i>

623
00:25:23,130 --> 00:25:24,566
<i>I think it should be a draw.</i>

624
00:25:26,307 --> 00:25:28,657
<i>But he kept on trying</i>
<i>to win for hours.</i>

625
00:25:32,182 --> 00:25:33,401
[HORSE NEIGHS]

626
00:25:35,359 --> 00:25:38,319
<i>Finally, he tried</i>
<i>one last cheap trick.</i>

627
00:25:42,541 --> 00:25:44,455
<i>All I had to do</i>
<i>was give away my queen.</i>

628
00:25:44,499 --> 00:25:45,674
<i>Then it would be stalemate.</i>

629
00:25:47,023 --> 00:25:48,634
<i>But I was so tired,</i>

630
00:25:48,677 --> 00:25:50,157
<i>I thought it was inevitable</i>
<i>I was going to be checkmated.</i>

631
00:25:52,289 --> 00:25:53,508
<i>And so I resigned.</i>

632
00:25:57,294 --> 00:25:59,558
<i>He jumped up.</i>
<i>Just started laughing.</i>

633
00:25:59,601 --> 00:26:00,559
[LAUGHING]

634
00:26:01,777 --> 00:26:02,909
<i>And he went,</i>

635
00:26:02,952 --> 00:26:04,171
<i>"Why have you resigned?</i>
<i>It's a draw."</i>

636
00:26:04,214 --> 00:26:05,346
<i>And he immediately,</i>
<i>with a flourish,</i>

637
00:26:05,389 --> 00:26:06,652
<i>sort of showed me</i>
<i>the drawing move.</i>

638
00:26:09,045 --> 00:26:12,396
<i>I felt so sick to my stomach.</i>

639
00:26:12,440 --> 00:26:14,137
<i>It made me think of</i>
<i>the rest of that tournament.</i>

640
00:26:14,181 --> 00:26:16,662
<i>Like, are we wasting</i>
<i>our minds?</i>

641
00:26:16,705 --> 00:26:19,708
<i>Is this the best use</i>
<i>of all this brain power?</i>

642
00:26:19,752 --> 00:26:22,363
<i>Everybody's, collectively,</i>
<i>in that building?</i>

643
00:26:22,406 --> 00:26:24,060
<i>If you could somehow plug in</i>

644
00:26:24,104 --> 00:26:27,542
<i>those 300 brains</i>
<i>into a system,</i>

645
00:26:27,586 --> 00:26:29,022
<i>you might be able</i>
<i>to solve cancer</i>

646
00:26:29,065 --> 00:26:30,501
<i>with that level</i>
<i>of brain power.</i>

647
00:26:31,633 --> 00:26:33,504
<i>This intuitive feeling</i>
<i>came over me</i>

648
00:26:33,548 --> 00:26:35,071
<i>that although I love chess,</i>

649
00:26:35,115 --> 00:26:38,335
<i>this is not the right thing</i>
<i>to spend my whole life on.</i>

650
00:26:51,479 --> 00:26:53,089
LEGG: <i>Demis and myself,</i>

651
00:26:53,133 --> 00:26:56,092
<i>our plan was always</i>
<i>to fill DeepMind</i>

652
00:26:56,136 --> 00:26:57,224
<i>with some of the most</i>

653
00:26:57,267 --> 00:26:59,226
<i>brilliant scientists</i>
<i>in the world.</i>

654
00:26:59,269 --> 00:27:01,054
<i>So we had the human brains</i>

655
00:27:01,097 --> 00:27:04,927
<i>necessary to create</i>
<i>an AGI system.</i>

656
00:27:04,971 --> 00:27:09,279
<i>By definition, the "G"</i>
<i>in AGI is about generality.</i>

657
00:27:09,323 --> 00:27:13,109
<i>What I imagine is being able</i>
<i>to talk to an agent,</i>

658
00:27:13,153 --> 00:27:15,198
<i>the agent can talk back,</i>

659
00:27:15,242 --> 00:27:18,898
<i>and the agent is able to solve</i>
<i>novel problems</i>

660
00:27:18,941 --> 00:27:20,595
<i>that it hasn't seen before.</i>

661
00:27:20,639 --> 00:27:22,728
<i>That's a really key part</i>
<i>of human intelligence,</i>

662
00:27:22,771 --> 00:27:24,468
<i>and it's that</i>
<i>cognitive breadth</i>

663
00:27:24,512 --> 00:27:27,733
<i>and flexibility</i>
<i>that's incredible.</i>

664
00:27:27,776 --> 00:27:29,473
<i>The only natural</i>
<i>general intelligence</i>

665
00:27:29,517 --> 00:27:30,910
<i>we know of as humans,</i>

666
00:27:30,953 --> 00:27:33,434
<i>we obviously learn a lot</i>
<i>from our environment.</i>

667
00:27:33,477 --> 00:27:35,871
<i>So we think that</i>
<i>simulated environments</i>

668
00:27:35,915 --> 00:27:38,874
<i>are one of the ways</i>
<i>to create an AGI.</i>

669
00:27:40,528 --> 00:27:42,356
SIMON CARTER:
<i>The very early humans</i>

670
00:27:42,399 --> 00:27:44,314
<i>were having to solve</i>
<i>logic problems.</i>

671
00:27:44,358 --> 00:27:46,752
<i>They were having to solve</i>
<i>navigation, memory,</i>

672
00:27:46,795 --> 00:27:48,971
<i>and we evolved</i>
<i>in that environment.</i>

673
00:27:50,364 --> 00:27:52,496
If we can create
a virtual recreation

674
00:27:52,540 --> 00:27:54,629
of that kind of environment,

675
00:27:54,673 --> 00:27:56,326
that's the perfect
testing ground

676
00:27:56,370 --> 00:27:57,458
and training ground

677
00:27:57,501 --> 00:27:59,329
for everything
we do at DeepMind.

678
00:28:04,247 --> 00:28:05,727
GUY SIMMONS:
<i>What they were doing here</i>

679
00:28:05,771 --> 00:28:09,252
<i>was creating environments</i>
<i>for childlike beings,</i>

680
00:28:09,296 --> 00:28:11,690
<i>the agents to exist</i>
<i>within and play.</i>

681
00:28:12,429 --> 00:28:13,648
That just sounded like

682
00:28:13,692 --> 00:28:16,782
the most interesting thing
in all the world.

683
00:28:16,825 --> 00:28:19,132
SHANAHAN: <i>A child</i>
<i>learns by tearing things up</i>

684
00:28:19,175 --> 00:28:20,655
<i>and then throwing food around</i>

685
00:28:20,699 --> 00:28:23,353
<i>and getting a response</i>
<i>from mommy or daddy.</i>

686
00:28:23,397 --> 00:28:25,616
This seems like an important
idea to incorporate

687
00:28:25,660 --> 00:28:27,880
in the way you train an agent.

688
00:28:27,923 --> 00:28:30,970
RESEARCHER 1: The humanoid
is supposed to stand up.

689
00:28:31,013 --> 00:28:32,972
As his center
of gravity rises,

690
00:28:33,015 --> 00:28:34,408
it gets more points.

691
00:28:37,454 --> 00:28:38,804
You have a reward

692
00:28:38,847 --> 00:28:40,849
and the agent
learns from the reward,

693
00:28:40,893 --> 00:28:43,373
<i>like, you do something well,</i>
<i>you get a positive reward.</i>

694
00:28:43,417 --> 00:28:47,508
<i>You do something bad,</i>
<i>you get a negative reward.</i>

695
00:28:47,551 --> 00:28:49,379
RESEARCHER 2: [EXCLAIMS]
It looks like it's standing.

696
00:28:50,859 --> 00:28:52,165
It's still a bit drunk.

697
00:28:52,208 --> 00:28:53,644
RESEARCHER 1:
It likes to walk backwards.

698
00:28:53,688 --> 00:28:55,342
RESEARCHER 2: [CHUCKLES] Yeah.

699
00:28:55,385 --> 00:28:57,518
The whole algorithm
is trying to optimize

700
00:28:57,561 --> 00:28:59,694
for receiving as much rewards
as possible,

701
00:28:59,738 --> 00:29:02,305
and it's found that
walking backwards,

702
00:29:02,349 --> 00:29:05,352
it's good enough
to get very good scores.

703
00:29:07,746 --> 00:29:09,573
RAIA HADSELL:
<i>When we learn to navigate,</i>

704
00:29:09,617 --> 00:29:11,271
<i>when we learn to get around</i>
<i>in our world,</i>

705
00:29:11,314 --> 00:29:13,490
<i>we don't start with maps.</i>

706
00:29:13,534 --> 00:29:16,319
<i>We just start</i>
<i>with our own exploration,</i>

707
00:29:16,363 --> 00:29:18,017
adventuring off
across the park,

708
00:29:18,060 --> 00:29:21,890
without our parents
by our side,

709
00:29:21,934 --> 00:29:24,327
or finding our way home
from school when we're young.

710
00:29:24,371 --> 00:29:25,546
[FAST ELECTRONIC
MUSIC PLAYING]

711
00:29:26,939 --> 00:29:28,723
HADSELL: <i>A few of us</i>
<i>came up with this idea</i>

712
00:29:28,767 --> 00:29:31,987
<i>that if we had an environment</i>
<i>where a simulated robot</i>

713
00:29:32,031 --> 00:29:33,728
<i>just had to run forward,</i>

714
00:29:33,772 --> 00:29:36,296
<i>we could put all sorts of</i>
<i>obstacles in its way</i>

715
00:29:36,339 --> 00:29:38,211
<i>and see if it could manage</i>
<i>to navigate</i>

716
00:29:38,254 --> 00:29:40,474
<i>different types of terrain.</i>

717
00:29:40,517 --> 00:29:43,042
The idea would be like
a parkour challenge.

718
00:29:46,393 --> 00:29:48,743
<i>It's not graceful,</i>

719
00:29:48,787 --> 00:29:51,833
<i>but was never trained to hold</i>
<i>a glass whilst it was running</i>

720
00:29:51,877 --> 00:29:53,052
<i>and not spill water.</i>

721
00:29:54,183 --> 00:29:55,706
You set this objective
that says,

722
00:29:55,750 --> 00:29:58,231
"Just move forward,
forward velocity,

723
00:29:58,274 --> 00:30:00,581
"and you'll get
a reward for that."

724
00:30:00,624 --> 00:30:02,670
<i>And the learning algorithm</i>
<i>figures out</i>

725
00:30:02,713 --> 00:30:05,412
<i>how to move</i>
<i>this complex set of joints.</i>

726
00:30:06,152 --> 00:30:07,370
<i>That's the power of</i>

727
00:30:07,414 --> 00:30:10,069
<i>reward-based</i>
<i>reinforcement learning.</i>

728
00:30:10,112 --> 00:30:12,767
SILVER: <i>Our goal</i>
<i>is to try and build agents</i>

729
00:30:12,811 --> 00:30:15,770
<i>which, we drop them in,</i>
<i>they know nothing,</i>

730
00:30:15,814 --> 00:30:18,381
<i>they get to play around in </i>
<i>whatever problem you give them</i>

731
00:30:18,425 --> 00:30:22,342
<i>and eventually figure out how</i>
<i>to solve it for themselves.</i>

732
00:30:22,385 --> 00:30:24,823
Now we want something
which can do that

733
00:30:24,866 --> 00:30:27,390
in as many different types
of problems as possible.

734
00:30:29,262 --> 00:30:32,918
<i>A human needs diverse skills</i>
<i>to interact with the world.</i>

735
00:30:32,961 --> 00:30:35,050
<i>How to deal</i>
<i>with complex images,</i>

736
00:30:35,094 --> 00:30:37,879
<i>how to manipulate</i>
<i>thousands of things at once,</i>

737
00:30:37,923 --> 00:30:40,447
<i>how to deal</i>
<i>with missing information.</i>

738
00:30:40,490 --> 00:30:42,014
<i>We think all of these things</i>
<i>together</i>

739
00:30:42,057 --> 00:30:45,278
<i>are represented </i>
<i>by this game called</i><i>StarCraft.</i>

740
00:30:45,321 --> 00:30:47,280
All it's being trained
to do is,

741
00:30:47,323 --> 00:30:50,457
given this situation,
this screen,

742
00:30:50,500 --> 00:30:51,850
what would a human do?

743
00:30:51,893 --> 00:30:55,244
<i>We took inspiration from</i>
<i>large language models</i>

744
00:30:55,288 --> 00:30:57,638
where you simply train
a model

745
00:30:57,681 --> 00:30:59,553
to predict the next word,

746
00:31:03,731 --> 00:31:05,472
<i>which is exactly the same as</i>

747
00:31:05,515 --> 00:31:07,735
<i>predict the next</i>
StarCraft <i>move.</i>

748
00:31:07,778 --> 00:31:08,954
SILVER: <i>Unlike chess or Go,</i>

749
00:31:08,997 --> 00:31:11,217
<i>where players take turns</i>
<i>to make moves,</i>

750
00:31:11,260 --> 00:31:14,133
<i>in</i>StarCraft <i>there's a</i>
<i>continuous flow of decisions.</i>

751
00:31:15,134 --> 00:31:16,483
<i>On top of that,</i>

752
00:31:16,526 --> 00:31:18,659
<i>you can't even see</i>
<i>what the opponent is doing.</i>

753
00:31:18,702 --> 00:31:20,879
<i>There is no longer</i>
<i>a clear definition</i>

754
00:31:20,922 --> 00:31:22,315
of what it means
to play the best way.

755
00:31:22,358 --> 00:31:23,925
It depends on
what your opponent does.

756
00:31:23,969 --> 00:31:25,492
HADSELL: <i>This is the way</i>
<i>that we'll get to</i>

757
00:31:25,535 --> 00:31:27,494
<i>a much more fluid,</i>

758
00:31:27,537 --> 00:31:31,672
more natural, faster,
more reactive agent.

759
00:31:31,715 --> 00:31:33,021
ORIOL VINYALS:
<i>This is a huge challenge</i>

760
00:31:33,065 --> 00:31:35,415
<i>and let's see how far</i>
<i>we can push.</i>

761
00:31:35,458 --> 00:31:36,459
TIM LILLICRAP: Oh!

762
00:31:36,503 --> 00:31:38,200
Holy monkey!

763
00:31:38,244 --> 00:31:40,376
<i>I'm a pretty</i>
<i>low-level amateur.</i>

764
00:31:40,420 --> 00:31:42,857
I'm okay, but I'm
a pretty low-level amateur.

765
00:31:42,901 --> 00:31:45,991
These agents have
a long ways to go.

766
00:31:46,034 --> 00:31:48,515
HASSABIS: <i>We couldn't</i>
<i>beat someone of Tim's level.</i>

767
00:31:48,558 --> 00:31:50,430
<i>You know, that was</i>
<i>a little bit alarming.</i>

768
00:31:50,473 --> 00:31:51,997
LILLICRAP:
<i>At that point, it felt like</i>

769
00:31:52,040 --> 00:31:53,520
<i>it was going to be, like,</i>
<i>a really big long challenge,</i>

770
00:31:53,563 --> 00:31:55,000
<i>maybe a couple of years.</i>

771
00:31:58,177 --> 00:32:01,832
VINYALS: <i>Dani is the best</i>
DeepMind StarCraft 2 <i>player.</i>

772
00:32:01,876 --> 00:32:05,097
I've been playing the agent
every day for a few weeks now.

773
00:32:07,186 --> 00:32:08,883
<i>I could feel that the agent</i>

774
00:32:08,927 --> 00:32:11,103
<i>was getting better</i>
<i>really fast.</i>

775
00:32:11,146 --> 00:32:13,366
[CHEERING, LAUGHTER]

776
00:32:13,409 --> 00:32:15,020
Wow, we beat Danny.
That, for me,

777
00:32:15,063 --> 00:32:16,935
was already
like a huge achievement.

778
00:32:18,284 --> 00:32:19,372
HASSABIS: <i>The next step is</i>

779
00:32:19,415 --> 00:32:21,722
<i>we're going to book in</i>
<i>a pro to play.</i>

780
00:32:23,071 --> 00:32:24,203
[KEYBOARD TAPPING]

781
00:32:27,032 --> 00:32:28,250
[GROANS]

782
00:32:28,294 --> 00:32:30,513
[CHEERING, WHOOPING]

783
00:32:32,994 --> 00:32:35,562
[CHEERING, WHOOPING]

784
00:32:35,605 --> 00:32:37,868
- [LAUGHS]
- [PEOPLE CLAPPING]

785
00:32:42,003 --> 00:32:44,049
It feels a bit unfair.
All you guys against me.

786
00:32:44,092 --> 00:32:45,572
[ALL LAUGH]

787
00:32:45,615 --> 00:32:46,965
HASSABIS: <i>We're way</i>
<i>ahead of what I thought</i>

788
00:32:47,008 --> 00:32:49,402
<i>we would do, given where</i>
<i>we were two months ago.</i>

789
00:32:49,445 --> 00:32:50,794
Just trying to digest it all,
actually.

790
00:32:50,838 --> 00:32:52,753
But it's very, very cool.

791
00:32:52,796 --> 00:32:54,146
SILVER: <i>Now we're in</i>
<i>a position where</i>

792
00:32:54,189 --> 00:32:56,061
<i>we can finally share</i>
<i>the work that we've done</i>

793
00:32:56,104 --> 00:32:57,192
<i>with the public.</i>

794
00:32:57,236 --> 00:32:58,585
This is a big step.

795
00:32:58,628 --> 00:33:00,674
We are really putting
ourselves on the line here.

796
00:33:00,717 --> 00:33:02,589
- Take it away. Cheers.
- Thank you.

797
00:33:02,632 --> 00:33:04,460
We're going to be live
from London.

798
00:33:04,504 --> 00:33:05,722
It's happening.

799
00:33:08,638 --> 00:33:10,597
ANNOUNCER 1:
<i>Welcome to London.</i>

800
00:33:10,640 --> 00:33:13,252
<i>We are going to have</i>
<i>a live exhibition match,</i>

801
00:33:13,295 --> 00:33:15,341
<i>MaNa against AlphaStar.</i>

802
00:33:15,384 --> 00:33:17,169
[CHEERING, APPLAUSE]

803
00:33:18,344 --> 00:33:19,998
<i>At this point now,</i>

804
00:33:20,041 --> 00:33:23,827
<i>AlphaStar, 10 and 0</i>
<i>against professional gamers.</i>

805
00:33:23,871 --> 00:33:25,873
<i>Any thoughts</i>
<i>before we get into this game?</i>

806
00:33:25,916 --> 00:33:27,483
VINYALS: <i>I just want to see</i>
<i>a good game, yeah.</i>

807
00:33:27,527 --> 00:33:28,963
<i>I want to see a good game.</i>

808
00:33:29,007 --> 00:33:30,486
SILVER: <i>Absolutely,</i>
<i>good game. We're all excited.</i>

809
00:33:30,530 --> 00:33:33,011
ANNOUNCER: <i>All right. Let's</i>
<i>see what MaNa can pull off.</i>

810
00:33:34,969 --> 00:33:36,405
ANNOUNCER 2:
<i>AlphaStar is definitely</i>

811
00:33:36,449 --> 00:33:38,364
<i>dominating the pace</i>
<i>of this game.</i>

812
00:33:38,407 --> 00:33:41,106
[SPORADIC CHEERING]

813
00:33:41,149 --> 00:33:44,152
ANNOUNCER 1: <i>Wow. AlphaStar</i>
<i>is playing so smartly.</i>

814
00:33:44,196 --> 00:33:46,807
[LAUGHTER]

815
00:33:46,850 --> 00:33:48,461
<i>This really looks like</i>
<i>I'm watching</i>

816
00:33:48,504 --> 00:33:49,940
<i>a professional human gamer</i>

817
00:33:49,984 --> 00:33:51,290
<i>from the AlphaStar</i>
<i>point of view.</i>

818
00:33:53,031 --> 00:33:54,858
[KEYBOARD TAPPING]

819
00:33:57,252 --> 00:34:01,952
HASSABIS: <i>I hadn't really seen </i>
<i>a pro play</i><i>StarCraft </i><i>up close,</i>

820
00:34:01,996 --> 00:34:03,563
<i>and the 800 clicks per minute.</i>

821
00:34:03,606 --> 00:34:06,000
<i>I don't understand how anyone</i>
<i>can even click 800 times,</i>

822
00:34:06,044 --> 00:34:09,482
let alone doing
800 useful clicks.

823
00:34:09,525 --> 00:34:11,092
ANNOUNCER 1:
<i>Oh, another good hit.</i>

824
00:34:11,136 --> 00:34:13,094
- [ALL GROAN]
<i>- AlphaStar is just</i>

825
00:34:13,138 --> 00:34:14,617
<i>completely relentless.</i>

826
00:34:14,661 --> 00:34:16,141
SILVER: <i>We need to be careful</i>

827
00:34:16,184 --> 00:34:19,361
<i>because many of us grew up</i>
<i>as gamers and are gamers.</i>

828
00:34:19,405 --> 00:34:21,363
And so to us,
it's very natural

829
00:34:21,407 --> 00:34:23,800
to view games
as what they are,

830
00:34:23,844 --> 00:34:26,977
which is pure vehicles
for fun,

831
00:34:27,021 --> 00:34:29,719
<i>and not to see</i>
<i>that more militaristic side</i>

832
00:34:29,763 --> 00:34:32,853
<i>that the public might see</i>
<i>if they looked at this.</i>

833
00:34:32,896 --> 00:34:37,553
You can't look at gunpowder
and only make a firecracker.

834
00:34:37,597 --> 00:34:41,209
<i>All technologies inherently </i>
<i>point into certain directions.</i>

835
00:34:43,124 --> 00:34:44,691
MARGARET LEVI:
<i>I'm very worried about</i>

836
00:34:44,734 --> 00:34:46,606
<i>the certain ways in which AI</i>

837
00:34:46,649 --> 00:34:49,652
<i>will be used</i>
<i>for military purposes.</i>

838
00:34:51,306 --> 00:34:55,049
And that makes it even clearer
how important it is

839
00:34:55,093 --> 00:34:58,357
for our societies
to be in control

840
00:34:58,400 --> 00:35:01,055
<i>of these new technologies.</i>

841
00:35:01,099 --> 00:35:05,190
The potential for abuse
from AI will be significant.

842
00:35:05,233 --> 00:35:08,758
<i>Wars that occur faster</i>
<i>than humans can comprehend</i>

843
00:35:08,802 --> 00:35:11,065
<i>and more powerful</i>
<i>surveillance.</i>

844
00:35:12,458 --> 00:35:15,765
How do you keep power forever

845
00:35:15,809 --> 00:35:19,421
over something that's
much more powerful than you?

846
00:35:19,465 --> 00:35:21,380
[STEPHEN HAWKING SPEAKING]

847
00:35:43,053 --> 00:35:45,752
Technologies can be used
to do terrible things.

848
00:35:47,493 --> 00:35:50,452
<i>And technology can be used</i>
<i>to do wonderful things</i>

849
00:35:50,496 --> 00:35:52,150
<i>and solve</i>
<i>all kinds of problems.</i>

850
00:35:53,586 --> 00:35:54,978
When DeepMind
was acquired by Google...

851
00:35:55,022 --> 00:35:56,589
- Yeah.
- ...you got Google to promise

852
00:35:56,632 --> 00:35:58,025
that technology you developed
won't be used by the military

853
00:35:58,068 --> 00:35:59,418
- for surveillance.
- Right.

854
00:35:59,461 --> 00:36:00,593
- Yes.
- Tell us about that.

855
00:36:00,636 --> 00:36:03,161
I think technology
is neutral in itself,

856
00:36:03,204 --> 00:36:05,598
um, but how, you know,
we as a society

857
00:36:05,641 --> 00:36:07,382
or humans and companies
and other things,

858
00:36:07,426 --> 00:36:09,515
other entities and governments
decide to use it

859
00:36:09,558 --> 00:36:12,561
is what determines whether
things become good or bad.

860
00:36:12,605 --> 00:36:16,261
You know, I personally think
having autonomous weaponry

861
00:36:16,304 --> 00:36:17,479
is just a very bad idea.

862
00:36:19,177 --> 00:36:21,266
ANNOUNCER 1:
<i>AlphaStar is playing</i>

863
00:36:21,309 --> 00:36:24,094
<i>an extremely intelligent game</i>
<i>right now.</i>

864
00:36:24,138 --> 00:36:27,359
CUKIER: <i>There is an element to</i>
<i>what's being created</i>

865
00:36:27,402 --> 00:36:28,882
<i>at DeepMind in London</i>

866
00:36:28,925 --> 00:36:34,148
that does seem like
the Manhattan Project.

867
00:36:34,192 --> 00:36:37,586
<i>There's a relationship between</i>
<i>Robert Oppenheimer</i>

868
00:36:37,630 --> 00:36:39,675
<i>and Demis Hassabis</i>

869
00:36:39,719 --> 00:36:44,202
<i>in which they're unleashing</i>
<i>a new force upon humanity.</i>

870
00:36:44,245 --> 00:36:46,204
ANNOUNCER 1:
<i>MaNa is fighting back, though.</i>

871
00:36:46,247 --> 00:36:48,162
Oh, man!

872
00:36:48,206 --> 00:36:50,208
HASSABIS:
<i>I think that Oppenheimer</i>

873
00:36:50,251 --> 00:36:52,471
<i>and some of the other leaders</i>
<i>of that project got caught up</i>

874
00:36:52,514 --> 00:36:54,908
<i>in the excitement</i>
<i>of building the technology</i>

875
00:36:54,951 --> 00:36:56,170
<i>and seeing if it was possible.</i>

876
00:36:56,214 --> 00:36:58,520
ANNOUNCER 1:
<i>Where is AlphaStar?</i>

877
00:36:58,564 --> 00:36:59,782
<i>Where is AlphaStar?</i>

878
00:36:59,826 --> 00:37:01,958
<i>I don't see AlphaStar's units</i>
<i>anywhere.</i>

879
00:37:02,002 --> 00:37:03,525
HASSABIS: <i>They did not think</i>
<i>carefully enough</i>

880
00:37:03,569 --> 00:37:07,312
<i>about the morals of what</i>
<i>they were doing early enough.</i>

881
00:37:07,355 --> 00:37:08,965
<i>What we should do</i>
<i>as scientists</i>

882
00:37:09,009 --> 00:37:11,011
<i>with powerful new technologies</i>

883
00:37:11,054 --> 00:37:13,883
<i>is try and understand it in</i>
<i>controlled conditions first.</i>

884
00:37:14,928 --> 00:37:16,799
ANNOUNCER 1: <i>And that is that.</i>

885
00:37:16,843 --> 00:37:19,411
<i>MaNa has defeated AlphaStar.</i>

886
00:37:29,551 --> 00:37:31,336
I mean, my honest feeling is
that I think it is

887
00:37:31,379 --> 00:37:33,207
a fair representation
of where we are.

888
00:37:33,251 --> 00:37:35,949
And I think that part feels...
feels okay.

889
00:37:35,992 --> 00:37:37,429
- I'm very happy for you.
- I'm happy.

890
00:37:37,472 --> 00:37:38,865
So well... well done.

891
00:37:38,908 --> 00:37:40,867
<i>My view is that the approach</i>
<i>to building technology</i>

892
00:37:40,910 --> 00:37:43,348
<i>which is embodied by</i>
<i>move fast and break things,</i>

893
00:37:43,391 --> 00:37:46,220
<i>is exactly what</i>
<i>we should not be doing,</i>

894
00:37:46,264 --> 00:37:47,961
<i>because you can't afford</i>
<i>to break things</i>

895
00:37:48,004 --> 00:37:49,049
<i>and then fix them afterwards.</i>

896
00:37:49,092 --> 00:37:50,398
- Cheers.
- Thank you so much.

897
00:37:50,442 --> 00:37:52,008
Yeah, get... get some rest.
You did really well.

898
00:37:52,052 --> 00:37:53,923
- Cheers, yeah?
- Thank you for having us.

899
00:38:01,627 --> 00:38:03,281
[ELECTRONIC MUSIC PLAYING]

900
00:38:04,238 --> 00:38:05,500
HASSABIS: <i>When I was eight,</i>

901
00:38:05,544 --> 00:38:06,849
<i>I bought my first computer</i>

902
00:38:06,893 --> 00:38:09,548
<i>with the winnings</i>
<i>from a chess tournam</i>ent.

903
00:38:09,591 --> 00:38:11,158
<i>I sort of had this intuition</i>

904
00:38:11,201 --> 00:38:13,726
<i>that computers</i>
<i>are this magical device</i>

905
00:38:13,769 --> 00:38:15,902
<i>that can extend</i>
<i>the power of the mind.</i>

906
00:38:15,945 --> 00:38:17,382
<i>I had a couple</i>
<i>of school friends,</i>

907
00:38:17,425 --> 00:38:19,166
<i>and we used to have</i>
<i>a hacking club,</i>

908
00:38:19,209 --> 00:38:21,908
<i>writing code, making games.</i>

909
00:38:26,260 --> 00:38:27,827
<i>And then over</i>
<i>the summer holidays,</i>

910
00:38:27,870 --> 00:38:29,219
<i>I'd spend the whole day</i>

911
00:38:29,263 --> 00:38:31,526
<i>flicking through</i>
<i>games magazines.</i>

912
00:38:31,570 --> 00:38:33,441
<i>And one day I noticed</i>
<i>there was a competition</i>

913
00:38:33,485 --> 00:38:35,878
<i>to write an original version</i>
<i>of Space Invaders.</i>

914
00:38:35,922 --> 00:38:39,621
<i>And the winner won a job</i>
<i>at Bullfrog.</i>

915
00:38:39,665 --> 00:38:42,320
<i>Bullfrog at the time was the</i>
<i>best game development house</i>

916
00:38:42,363 --> 00:38:43,756
<i>in all of Europe.</i>

917
00:38:43,799 --> 00:38:45,279
<i>You know, I really wanted</i>
<i>to work at this place</i>

918
00:38:45,323 --> 00:38:48,587
<i>and see how they build games.</i>

919
00:38:48,630 --> 00:38:50,415
NEWSCASTER: <i>Bullfrog,</i>
<i>based here in Guildford,</i>

920
00:38:50,458 --> 00:38:52,286
<i>began with a big idea.</i>

921
00:38:52,330 --> 00:38:54,680
<i>That idea turned into the game</i>
Populous,

922
00:38:54,723 --> 00:38:56,551
<i>which became</i>
<i>a global bestseller.</i>

923
00:38:56,595 --> 00:38:59,859
In the '90s, there was
no recruitment agencies.

924
00:38:59,902 --> 00:39:02,122
You couldn't go out and say,
you know,

925
00:39:02,165 --> 00:39:04,951
"Come and work
in the games industry."

926
00:39:04,994 --> 00:39:08,171
It was still not even
considered an industry.

927
00:39:08,215 --> 00:39:11,218
<i>So we came up with the idea</i>
<i>to have a competition</i>

928
00:39:11,261 --> 00:39:13,655
<i>and we got</i>
<i>a lot of applicants.</i>

929
00:39:14,700 --> 00:39:17,616
<i>And one of those was Demis's.</i>

930
00:39:17,659 --> 00:39:20,706
I can still remember clearly

931
00:39:20,749 --> 00:39:23,970
the day that Demis came in.

932
00:39:24,013 --> 00:39:27,147
<i>He walked in the door,</i>
<i>he looked about 12.</i>

933
00:39:28,670 --> 00:39:30,019
I thought, "Oh, my God,

934
00:39:30,063 --> 00:39:31,586
"what the hell are we going
to do with this guy?"

935
00:39:31,630 --> 00:39:32,979
I applied to Cambridge.

936
00:39:33,022 --> 00:39:35,373
I got in but they said
I was way too young.

937
00:39:35,416 --> 00:39:37,853
So...
So I needed to take a year off

938
00:39:37,897 --> 00:39:39,899
so I'd be at least 17
before I got there.

939
00:39:39,942 --> 00:39:42,771
<i>And that's when I decided</i>
<i>to spend that entire gap year</i>

940
00:39:42,815 --> 00:39:44,469
<i>working at Bullfrog.</i>

941
00:39:44,512 --> 00:39:46,166
<i>They couldn't even</i>
<i>legally employ me,</i>

942
00:39:46,209 --> 00:39:48,298
<i>so I ended up being paid</i>
<i>in brown paper envelopes.</i>

943
00:39:48,342 --> 00:39:49,343
[CHUCKLES]

944
00:39:50,823 --> 00:39:54,304
<i>I got a feeling of being</i>
<i>really at the cutting edge</i>

945
00:39:54,348 --> 00:39:58,047
<i>and how much fun that was</i>
<i>to invent things every day.</i>

946
00:39:58,091 --> 00:40:00,572
And then you know,
a few months later,

947
00:40:00,615 --> 00:40:03,662
maybe everyone... a million
people will be playing it.

948
00:40:03,705 --> 00:40:06,665
MOLYNEUX: <i>In those days</i>
<i>computer games had to evolve.</i>

949
00:40:06,708 --> 00:40:08,536
<i>There had to be new genres</i>

950
00:40:08,580 --> 00:40:11,757
<i>which were more</i>
<i>than just shooting things.</i>

951
00:40:11,800 --> 00:40:14,063
Wouldn't it be amazing
to have a game

952
00:40:14,107 --> 00:40:18,807
where you design and build
your own theme park?

953
00:40:18,851 --> 00:40:21,027
[GAME CHARACTERS SCREAMING]

954
00:40:22,594 --> 00:40:25,945
<i>Demis and I started to talk</i>
<i>about</i>Theme Park.

955
00:40:25,988 --> 00:40:28,904
<i>It allows the player</i>
<i>to build a world</i>

956
00:40:28,948 --> 00:40:31,864
<i>and see the consequences</i>
<i>of your choices</i>

957
00:40:31,907 --> 00:40:34,127
<i>that you've made</i>
<i>in that world.</i>

958
00:40:34,170 --> 00:40:36,085
HASSABIS: <i>A human player</i>
<i>set out the layout</i>

959
00:40:36,129 --> 00:40:38,566
<i>of the theme park and designed</i>
<i>the roller coaster</i>

960
00:40:38,610 --> 00:40:41,351
<i>and set the prices</i>
<i>in the chip shop.</i>

961
00:40:41,395 --> 00:40:43,615
<i>What I was working on was</i>
<i>the behaviors of the people.</i>

962
00:40:43,658 --> 00:40:45,138
<i>They were autonomous</i>

963
00:40:45,181 --> 00:40:47,314
<i>and that was the AI</i>
<i>in this case.</i>

964
00:40:47,357 --> 00:40:48,881
So what I was trying to do
was mimic

965
00:40:48,924 --> 00:40:51,013
interesting human behavior

966
00:40:51,057 --> 00:40:52,319
so that the simulation
would be

967
00:40:52,362 --> 00:40:54,582
more interesting
to interact with.

968
00:40:54,626 --> 00:40:56,541
MOLYNEUX: <i>Demis worked</i>
<i>on ridiculous things,</i>

969
00:40:56,584 --> 00:40:59,413
<i>like you could place down</i>
<i>these shops</i>

970
00:40:59,457 --> 00:41:03,591
<i>and if you put a shop too near</i>
<i>a very dangerous ride,</i>

971
00:41:03,635 --> 00:41:05,375
<i>then people on the ride</i>
<i>would throw up</i>

972
00:41:05,419 --> 00:41:08,030
<i>because they'd just eaten.</i>

973
00:41:08,074 --> 00:41:09,641
And then that would make
other people throw up

974
00:41:09,684 --> 00:41:12,121
when they saw the throwing-up
on the floor,

975
00:41:12,165 --> 00:41:14,559
so you then had to have
lots of sweepers

976
00:41:14,602 --> 00:41:17,823
<i>to quickly sweep it up</i>
<i>before the people saw it.</i>

977
00:41:17,866 --> 00:41:19,520
<i>That's the cool thing</i>
<i>about it.</i>

978
00:41:19,564 --> 00:41:22,784
<i>You as the player tinker with</i>
<i>it and then it reacts to you.</i>

979
00:41:22,828 --> 00:41:25,874
MOLYNEUX: <i>All those nuanced</i>
<i>simulation things he did</i>

980
00:41:25,918 --> 00:41:28,094
and that was an invention

981
00:41:28,137 --> 00:41:31,227
which never really
existed before.

982
00:41:31,271 --> 00:41:34,230
<i>It was</i>
<i>unbelievably successful.</i>

983
00:41:34,274 --> 00:41:35,710
DAVID GARDNER:
Theme Park <i>actually turned out</i>

984
00:41:35,754 --> 00:41:37,190
<i>to be a top ten title</i>

985
00:41:37,233 --> 00:41:39,932
and that was the first time
we were starting to see

986
00:41:39,975 --> 00:41:43,022
how AI could make
a difference.

987
00:41:43,065 --> 00:41:44,806
[BRASS BAND PLAYING]

988
00:41:46,155 --> 00:41:47,592
CARTER: <i>We were doing</i>
<i>some Christmas shopping</i>

989
00:41:47,635 --> 00:41:51,247
<i>and were waiting for the taxi</i>
<i>to take us home.</i>

990
00:41:51,291 --> 00:41:54,947
I have this very clear memory
of Demis talking about AI

991
00:41:54,990 --> 00:41:56,209
in a very different way,

992
00:41:56,252 --> 00:41:58,428
in a way that we didn't
commonly talk about.

993
00:41:58,472 --> 00:42:02,345
This idea of AI being useful
for other things

994
00:42:02,389 --> 00:42:04,086
other than entertainment.

995
00:42:04,130 --> 00:42:07,437
So being useful for, um,
helping the world

996
00:42:07,481 --> 00:42:10,310
and the potential of AI
to change the world.

997
00:42:10,353 --> 00:42:13,226
I just said to Demis,
"What is it you want to do?"

998
00:42:13,269 --> 00:42:14,532
And he said to me,

999
00:42:14,575 --> 00:42:16,795
"I want to be the person
that solves AI."

1000
00:42:22,670 --> 00:42:25,760
HASSABIS:
<i>Peter offered me £1 million</i>

1001
00:42:25,804 --> 00:42:27,675
<i>to not go to university.</i>

1002
00:42:30,199 --> 00:42:32,593
<i>But I had a plan</i>
<i>from the beginning.</i>

1003
00:42:32,637 --> 00:42:35,814
<i>And my plan was always</i>
<i>to go to Cambridge.</i>

1004
00:42:35,857 --> 00:42:36,902
I think a lot of
my schoolfriends

1005
00:42:36,945 --> 00:42:38,033
thought I was mad.

1006
00:42:38,077 --> 00:42:39,252
Why would you not...

1007
00:42:39,295 --> 00:42:40,688
I mean, £1 million,
that's a lot of money.

1008
00:42:40,732 --> 00:42:43,517
In the '90s,
that is a lot of money, right?

1009
00:42:43,561 --> 00:42:46,346
For a...
For a poor 17-year-old kid.

1010
00:42:46,389 --> 00:42:50,219
He's like this little seed
that's going to burst through,

1011
00:42:50,263 --> 00:42:53,658
and he's not going to be able
to do that at Bullfrog.

1012
00:42:56,443 --> 00:42:59,098
<i>I had to drop him off</i>
<i>at the train station</i>

1013
00:42:59,141 --> 00:43:02,580
<i>and I can still see</i>
<i>that picture</i>

1014
00:43:02,623 --> 00:43:07,019
of this little elven character
disappear down that tunnel.

1015
00:43:07,062 --> 00:43:09,804
That was an incredibly
sad moment.

1016
00:43:13,242 --> 00:43:14,635
HASSABIS:
<i>I had this romantic ideal</i>

1017
00:43:14,679 --> 00:43:16,942
<i>of what Cambridge</i>
<i>would be like,</i>

1018
00:43:16,985 --> 00:43:18,639
<i>1,000 years of history,</i>

1019
00:43:18,683 --> 00:43:21,033
<i>walking the same streets</i>
<i>that Turing,</i>

1020
00:43:21,076 --> 00:43:23,601
<i>Newton and Crick had walked.</i>

1021
00:43:23,644 --> 00:43:26,647
<i>I wanted to explore</i>
<i>the edge of the universe.</i>

1022
00:43:26,691 --> 00:43:27,735
[CHURCH BELLS TOLLING]

1023
00:43:29,084 --> 00:43:30,346
<i>When I got to Cambridge,</i>

1024
00:43:30,390 --> 00:43:32,653
<i>I'd basically been working</i>
<i>my whole life.</i>

1025
00:43:33,741 --> 00:43:35,090
<i>Every single summer,</i>

1026
00:43:35,134 --> 00:43:37,136
<i>I was either playing chess</i>
<i>professionally,</i>

1027
00:43:37,179 --> 00:43:39,704
<i>or I was working,</i>
<i>doing an internship.</i>

1028
00:43:39,747 --> 00:43:43,708
<i>So I was, like, "Right,</i>
<i>I am gonna have fun now</i>

1029
00:43:43,751 --> 00:43:46,711
<i>"and explore what it means</i>
<i>to be a normal teenager."</i>

1030
00:43:47,973 --> 00:43:50,192
[PEOPLE CHEERING, LAUGHING]

1031
00:43:50,236 --> 00:43:52,238
Come on! Go, boy, go!

1032
00:43:52,281 --> 00:43:54,022
TIM STEVENS: <i>It was work hard</i>
<i>and play hard.</i>

1033
00:43:54,066 --> 00:43:55,807
[ALL SINGING]

1034
00:43:55,850 --> 00:43:57,025
I first met Demis

1035
00:43:57,069 --> 00:43:59,201
because we both attended
Queens' College.

1036
00:44:00,115 --> 00:44:01,203
<i>Our group of friends,</i>

1037
00:44:01,247 --> 00:44:03,205
<i>we'd often drink beer</i>
<i>in the bar,</i>

1038
00:44:03,249 --> 00:44:04,946
<i>play table football.</i>

1039
00:44:04,990 --> 00:44:07,340
HASSABIS: <i>In the bar,</i>
<i>I used to play speed chess,</i>

1040
00:44:07,383 --> 00:44:09,255
<i>pieces flying off the board,</i>

1041
00:44:09,298 --> 00:44:11,083
<i>you know, the whole game</i>
<i>in one minute.</i>

1042
00:44:11,126 --> 00:44:12,301
Demis sat down opposite me.

1043
00:44:12,345 --> 00:44:13,563
And I looked at him
and I thought,

1044
00:44:13,607 --> 00:44:15,217
"I remember you
from when we were kids."

1045
00:44:15,261 --> 00:44:17,176
HASSABIS: <i>I had actually been</i>
<i>in the same chess tournament</i>

1046
00:44:17,219 --> 00:44:18,786
<i>as Dave in Ipswich,</i>

1047
00:44:18,830 --> 00:44:20,440
<i>where I used to go and try</i>
<i>and raid his local chess club</i>

1048
00:44:20,483 --> 00:44:22,703
<i>to win a bit of prize money.</i>

1049
00:44:22,747 --> 00:44:24,618
COPPIN: <i>We were studying</i>
<i>computer science.</i>

1050
00:44:24,662 --> 00:44:26,794
<i>Some people,</i>
<i>who at the age of 17</i>

1051
00:44:26,838 --> 00:44:28,404
would have come in and made
sure to tell everybody

1052
00:44:28,448 --> 00:44:29,492
everything about themselves.

1053
00:44:29,536 --> 00:44:30,972
<i>"Hey, I worked at Bullfrog</i>

1054
00:44:31,016 --> 00:44:33,018
<i>"and built the world's</i>
<i>most successful video game."</i>

1055
00:44:33,061 --> 00:44:34,715
<i>But he wasn't like that</i>
<i>at all.</i>

1056
00:44:34,759 --> 00:44:36,412
SILVER: <i>At Cambridge,</i>
<i>Demis and myself</i>

1057
00:44:36,456 --> 00:44:38,414
<i>both had an interest</i>
<i>in computational neuroscience</i>

1058
00:44:38,458 --> 00:44:40,242
and trying to understand
how computers and brains

1059
00:44:40,286 --> 00:44:42,636
intertwined
and linked together.

1060
00:44:42,680 --> 00:44:44,290
JOHN DAUGMAN:
<i>Both David and Demis</i>

1061
00:44:44,333 --> 00:44:46,422
<i>came to me for supervisions.</i>

1062
00:44:46,466 --> 00:44:49,774
It happens just by coincidence
that the year 1997,

1063
00:44:49,817 --> 00:44:51,645
their third and final year
at Cambridge,

1064
00:44:51,689 --> 00:44:55,301
was also the year when
the first chess grandmaster

1065
00:44:55,344 --> 00:44:56,781
was beaten by
a computer program.

1066
00:44:56,824 --> 00:44:58,260
[CAMERA SHUTTERS CLICKING]

1067
00:44:58,304 --> 00:45:00,088
NEWSCASTER: <i>Round one today</i>
<i>of a chess match</i>

1068
00:45:00,132 --> 00:45:03,701
<i>between the ranking</i>
<i>world champion Garry Kasparov</i>

1069
00:45:03,744 --> 00:45:06,007
<i>and an opponent named</i>
<i>Deep Blue</i>

1070
00:45:06,051 --> 00:45:10,490
<i>to test to see if the human</i>
<i>brain can outwit a machine.</i>

1071
00:45:10,533 --> 00:45:11,621
HASSABIS: <i>I remember the drama</i>

1072
00:45:11,665 --> 00:45:13,798
<i>of Kasparov</i>
<i>losing the last match.</i>

1073
00:45:13,841 --> 00:45:15,234
NEWSCASTER 2: <i>Whoa!</i>

1074
00:45:15,277 --> 00:45:17,192
<i>Kasparov has resigned!</i>

1075
00:45:17,236 --> 00:45:19,586
When Deep Blue
beat Garry Kasparov,

1076
00:45:19,629 --> 00:45:21,457
that was a real
watershed event.

1077
00:45:21,501 --> 00:45:23,155
HASSABIS:
<i>My main memory of it was</i>

1078
00:45:23,198 --> 00:45:25,331
<i>I wasn't that impressed</i>
<i>with Deep Blue.</i>

1079
00:45:25,374 --> 00:45:27,246
<i>I was more impressed</i>
<i>with Kasparov's mind.</i>

1080
00:45:27,289 --> 00:45:29,509
<i>That he could play chess</i>
<i>to this level,</i>

1081
00:45:29,552 --> 00:45:31,641
<i>where he could compete</i>
<i>on an equal footing</i>

1082
00:45:31,685 --> 00:45:33,252
<i>with the brute of a machine,</i>

1083
00:45:33,295 --> 00:45:35,167
<i>but of course, Kasparov can do</i>

1084
00:45:35,210 --> 00:45:36,951
<i>everything else humans can do,</i>
<i>too.</i>

1085
00:45:36,995 --> 00:45:38,257
<i>It was a huge achievement.</i>

1086
00:45:38,300 --> 00:45:39,388
<i>But the truth</i>
<i>of the matter was,</i>

1087
00:45:39,432 --> 00:45:40,868
<i>Deep Blue</i>
<i>could only play chess.</i>

1088
00:45:42,435 --> 00:45:44,524
<i>What we would regard</i>
<i>as intelligence</i>

1089
00:45:44,567 --> 00:45:46,874
<i>was missing from that system.</i>

1090
00:45:46,918 --> 00:45:49,834
<i>This idea of generality</i>
<i>and also learning.</i>

1091
00:45:53,751 --> 00:45:55,404
<i>Cambridge was amazing,</i>
<i>because of course, you know,</i>

1092
00:45:55,448 --> 00:45:56,666
<i>you're mixing with people</i>

1093
00:45:56,710 --> 00:45:58,233
<i>who are studying</i>
<i>many different subjects.</i>

1094
00:45:58,277 --> 00:46:01,410
SILVER: <i>There were scientists,</i>
<i>philosophers, artists...</i>

1095
00:46:01,454 --> 00:46:04,457
STEVENS: <i>...geologists,</i>
<i>biologists, ecologists.</i>

1096
00:46:04,500 --> 00:46:07,416
<i>You know, everybody is talking </i>
<i>about everything all the time.</i>

1097
00:46:07,460 --> 00:46:10,768
I was obsessed with
the protein folding problem.

1098
00:46:10,811 --> 00:46:13,248
HASSABIS: <i>Tim Stevens used</i>
<i>to talk obsessively,</i>

1099
00:46:13,292 --> 00:46:15,381
almost like religiously
about this problem,

1100
00:46:15,424 --> 00:46:17,165
protein folding problem.

1101
00:46:17,209 --> 00:46:18,863
STEVENS:
<i>Proteins are, you know,</i>

1102
00:46:18,906 --> 00:46:22,083
<i>one of the most beautiful and</i>
<i>elegant things about biology.</i>

1103
00:46:22,127 --> 00:46:24,738
<i>They are the machines of life.</i>

1104
00:46:24,782 --> 00:46:27,001
They build everything,
they control everything,

1105
00:46:27,045 --> 00:46:29,569
they're why biology works.

1106
00:46:29,612 --> 00:46:32,659
<i>Proteins are made from strings</i>
<i>of amino acids</i>

1107
00:46:32,702 --> 00:46:37,055
<i>that fold up to create</i>
<i>a protein structure.</i>

1108
00:46:37,098 --> 00:46:39,884
<i>If we can predict</i>
<i>the structure of proteins</i>

1109
00:46:39,927 --> 00:46:43,104
<i>from just their amino acid</i>
<i>sequences,</i>

1110
00:46:43,148 --> 00:46:46,107
<i>then a new protein</i>
<i>to cure cancer</i>

1111
00:46:46,151 --> 00:46:49,415
<i>or break down plastic</i>
<i>to help the environment</i>

1112
00:46:49,458 --> 00:46:50,808
<i>is definitely something</i>

1113
00:46:50,851 --> 00:46:52,940
<i>that you could begin</i>
<i>to think about.</i>

1114
00:46:53,941 --> 00:46:55,029
I kind of thought,

1115
00:46:55,073 --> 00:46:58,293
"Well, is a human being
clever enough

1116
00:46:58,337 --> 00:46:59,991
"to actually fold a protein?"

1117
00:47:00,034 --> 00:47:02,080
<i>We can't work it out.</i>

1118
00:47:02,123 --> 00:47:04,082
JOHN MOULT: <i>Since the 1960s,</i>

1119
00:47:04,125 --> 00:47:05,953
<i>we thought that in principle,</i>

1120
00:47:05,997 --> 00:47:08,913
<i>if I know what the amino acid</i>
<i>sequence of a protein is,</i>

1121
00:47:08,956 --> 00:47:11,437
<i>I should be able to compute</i>
<i>what the structure's like.</i>

1122
00:47:11,480 --> 00:47:13,700
So, if you could
just press a button,

1123
00:47:13,743 --> 00:47:16,311
and they'd all come
popping out, that would be...

1124
00:47:16,355 --> 00:47:18,009
that would have some impact.

1125
00:47:20,272 --> 00:47:21,577
HASSABIS: <i>It stuck in my mind.</i>

1126
00:47:21,621 --> 00:47:23,405
<i>"Oh, this is</i>
<i>a very interesting problem."</i>

1127
00:47:23,449 --> 00:47:26,844
<i>And it felt to me</i>
<i>like it would be solvable.</i>

1128
00:47:26,887 --> 00:47:29,934
<i>But I thought</i>
<i>it would need AI to do it.</i>

1129
00:47:31,500 --> 00:47:34,025
<i>If we could just solve</i>
<i>protein folding,</i>

1130
00:47:34,068 --> 00:47:35,635
<i>it could change the world.</i>

1131
00:47:50,868 --> 00:47:52,826
HASSABIS: <i>Ever since</i>
<i>I was a student at Cambridge,</i>

1132
00:47:54,001 --> 00:47:55,611
<i>I've never</i>
<i>stopped thinking about</i>

1133
00:47:55,655 --> 00:47:57,135
<i>the protein folding problem.</i>

1134
00:47:59,789 --> 00:48:02,792
<i>If you were</i>
<i>to solve protein folding,</i>

1135
00:48:02,836 --> 00:48:05,665
<i>then the potential</i>
<i>to help solve problems like</i>

1136
00:48:05,708 --> 00:48:09,669
<i>Alzheimer's, dementia</i>
<i>and drug discovery is huge.</i>

1137
00:48:09,712 --> 00:48:11,671
<i>Solving disease is probably</i>

1138
00:48:11,714 --> 00:48:13,325
<i>the most major impact</i>
<i>we could have.</i>

1139
00:48:13,368 --> 00:48:14,587
[CLICKS MOUSE]

1140
00:48:15,457 --> 00:48:16,676
<i>Thousands of very smart people</i>

1141
00:48:16,719 --> 00:48:18,765
<i>have tried</i>
<i>to solve protein folding.</i>

1142
00:48:18,808 --> 00:48:20,985
<i>I just think now</i>
<i>is the right time</i>

1143
00:48:21,028 --> 00:48:22,508
<i>for AI to crack it.</i>

1144
00:48:22,551 --> 00:48:24,292
[THRILLING MUSIC PLAYING]

1145
00:48:24,336 --> 00:48:26,512
[INDISTINCT CONVERSATION]

1146
00:48:26,555 --> 00:48:28,383
RICHARD EVANS: <i>We needed</i>
<i>a reasonable way</i>

1147
00:48:28,427 --> 00:48:29,515
<i>to apply machine learning</i>

1148
00:48:29,558 --> 00:48:30,516
<i>to the protein folding</i>
<i>problem.</i>

1149
00:48:30,559 --> 00:48:32,387
[CLICKING MOUSE]

1150
00:48:32,431 --> 00:48:35,173
<i>We came across</i>
<i>this Foldit game.</i>

1151
00:48:35,216 --> 00:48:38,785
<i>The goal is to move around</i>
<i>this 3D model of a protein</i>

1152
00:48:38,828 --> 00:48:41,701
<i>and you get a score</i>
<i>every time you move it.</i>

1153
00:48:41,744 --> 00:48:43,050
The more accurate
you make these structures,

1154
00:48:43,094 --> 00:48:45,531
the more useful
they will be to biologists.

1155
00:48:46,227 --> 00:48:47,489
<i>I spent a few days</i>

1156
00:48:47,533 --> 00:48:48,838
<i>just kind of seeing</i>
<i>how well we could do.</i>

1157
00:48:48,882 --> 00:48:50,623
[GAME DINGING]

1158
00:48:50,666 --> 00:48:52,407
<i>We did reasonably well.</i>

1159
00:48:52,451 --> 00:48:53,843
But even if you were

1160
00:48:53,887 --> 00:48:55,280
the world's
best Foldit player,

1161
00:48:55,323 --> 00:48:57,499
you wouldn't
solve protein folding.

1162
00:48:57,543 --> 00:48:59,501
<i>That's why we had</i>
<i>to move beyond the game.</i>

1163
00:48:59,545 --> 00:49:00,720
HASSABIS: <i>Games</i>
<i>are always just</i>

1164
00:49:00,763 --> 00:49:03,723
<i>the proving ground</i>
<i>for our algorithms.</i>

1165
00:49:03,766 --> 00:49:07,727
<i>The ultimate goal was not just</i>
<i>to crack Go and StarCraft.</i>

1166
00:49:07,770 --> 00:49:10,034
<i>It was to crack</i>
<i>real-world challenges.</i>

1167
00:49:10,904 --> 00:49:13,037
[THRILLING MUSIC CONTINUES]

1168
00:49:16,127 --> 00:49:18,520
JOHN JUMPER: <i>I remember</i>
<i>hearing this rumor</i>

1169
00:49:18,564 --> 00:49:21,175
<i>that Demis was</i>
<i>getting into proteins.</i>

1170
00:49:21,219 --> 00:49:23,743
<i>I talked to some people</i>
<i>at DeepMind and I would ask,</i>

1171
00:49:23,786 --> 00:49:25,049
<i>"So are you doing</i>
<i>protein folding?"</i>

1172
00:49:25,092 --> 00:49:26,920
<i>And they would</i>
<i>artfully change the subject.</i>

1173
00:49:26,964 --> 00:49:30,097
<i>And when that happened twice,</i>
<i>I pretty much figured it out.</i>

1174
00:49:30,141 --> 00:49:32,839
<i>So I thought</i>
<i>I should submit a resume.</i>

1175
00:49:32,882 --> 00:49:35,668
HASSABIS: All right, everyone,
welcome to DeepMind.

1176
00:49:35,711 --> 00:49:37,626
I know some of you,
this may be your first week,

1177
00:49:37,670 --> 00:49:39,193
but I hope you all set...

1178
00:49:39,237 --> 00:49:40,890
JUMPER: <i>The really appealing</i>
<i>part for me about the job</i>

1179
00:49:40,934 --> 00:49:42,675
was this, like,
sense of connection

1180
00:49:42,718 --> 00:49:44,503
to the larger purpose.

1181
00:49:44,546 --> 00:49:45,591
HASSABIS: If we can crack

1182
00:49:45,634 --> 00:49:48,028
some fundamental problems
in science,

1183
00:49:48,072 --> 00:49:49,160
many other people

1184
00:49:49,203 --> 00:49:50,900
and other companies
and labs and so on

1185
00:49:50,944 --> 00:49:52,467
could build
on top of our work.

1186
00:49:52,511 --> 00:49:53,816
<i>This is your chance now</i>

1187
00:49:53,860 --> 00:49:55,818
<i>to add your chapter</i>
<i>to this story.</i>

1188
00:49:55,862 --> 00:49:57,298
JUMPER: <i>When I arrived,</i>

1189
00:49:57,342 --> 00:49:59,605
<i>I was definitely</i>[CHUCKLES]
<i>quite a bit nervous.</i>

1190
00:49:59,648 --> 00:50:00,736
I'm still trying to keep...

1191
00:50:00,780 --> 00:50:02,912
<i>I haven't taken</i>
<i>any biology courses.</i>

1192
00:50:02,956 --> 00:50:05,393
We haven't spent
years of our lives

1193
00:50:05,437 --> 00:50:07,917
looking at these structures
and understanding them.

1194
00:50:07,961 --> 00:50:09,963
We are just going off the data

1195
00:50:10,007 --> 00:50:11,269
<i>and our machine learning</i>
<i>models.</i>

1196
00:50:12,705 --> 00:50:13,836
JUMPER: <i>In machine learning,</i>

1197
00:50:13,880 --> 00:50:15,795
<i>you train a network</i>
<i>like flashcards.</i>

1198
00:50:15,838 --> 00:50:18,798
<i>Here's the question.</i>
<i>Here's the answer.</i>

1199
00:50:18,841 --> 00:50:20,756
<i>Here's the question.</i>
<i>Here's the answer.</i>

1200
00:50:20,800 --> 00:50:22,323
<i>But in protein folding,</i>

1201
00:50:22,367 --> 00:50:25,457
we're not doing the kind
of standard task at DeepMind

1202
00:50:25,500 --> 00:50:28,155
<i>where you have unlimited data.</i>

1203
00:50:28,199 --> 00:50:30,766
<i>Your job is to get better</i>
<i>at chess or Go</i>

1204
00:50:30,810 --> 00:50:32,986
<i>and you can play</i>
<i>as many games of chess or Go</i>

1205
00:50:33,030 --> 00:50:34,814
<i>as your computers will allow.</i>

1206
00:50:35,510 --> 00:50:36,772
<i>With proteins,</i>

1207
00:50:36,816 --> 00:50:39,732
<i>we're sitting on</i>
<i>a very thick size of data</i>

1208
00:50:39,775 --> 00:50:41,995
<i>that's been determined</i>
<i>by a half century</i>

1209
00:50:42,039 --> 00:50:46,478
<i>of time-consuming experimental</i>
<i>methods in laboratories.</i>

1210
00:50:46,521 --> 00:50:49,698
<i>These painstaking methods</i>
<i>can take months or years</i>

1211
00:50:49,742 --> 00:50:52,353
<i>to determine</i>
<i>a single protein structure,</i>

1212
00:50:52,397 --> 00:50:55,791
<i>and sometimes, a structure</i>
<i>can never be determined.</i>

1213
00:50:55,835 --> 00:50:57,271
[TYPING]

1214
00:50:57,315 --> 00:51:00,274
<i>That's why we're working</i>
<i>with such small datasets</i>

1215
00:51:00,318 --> 00:51:02,233
<i>to train our algorithms.</i>

1216
00:51:02,276 --> 00:51:04,365
EWAN BIRNEY: <i>When DeepMind</i>
<i>started to explore</i>

1217
00:51:04,409 --> 00:51:05,975
<i>the folding problem,</i>

1218
00:51:06,019 --> 00:51:07,977
they were talking to us about
which datasets they were using

1219
00:51:08,021 --> 00:51:09,892
and what would be
the possibilities

1220
00:51:09,936 --> 00:51:11,633
if they did
solve this problem.

1221
00:51:12,373 --> 00:51:13,940
<i>Many people have tried,</i>

1222
00:51:13,983 --> 00:51:16,638
<i>and yet no one on the planet</i>
<i>has solved protein folding.</i>

1223
00:51:16,682 --> 00:51:18,205
[CHUCKLES]
I did think to myself,

1224
00:51:18,249 --> 00:51:19,946
"Well, you know, good luck."

1225
00:51:19,989 --> 00:51:22,731
JUMPER: If we can solve
the protein folding problem,

1226
00:51:22,775 --> 00:51:25,691
it would have an incredible
kind of medical relevance.

1227
00:51:25,734 --> 00:51:27,736
HASSABIS:
<i>This is the cycle of science.</i>

1228
00:51:27,780 --> 00:51:30,043
<i>You do a huge amount</i>
<i>of exploration,</i>

1229
00:51:30,087 --> 00:51:31,914
<i>and then you go</i>
<i>into exploitation mode,</i>

1230
00:51:31,958 --> 00:51:33,568
and you focus and you see

1231
00:51:33,612 --> 00:51:35,353
how good
are those ideas, really?

1232
00:51:35,396 --> 00:51:36,528
<i>And there's nothing better</i>

1233
00:51:36,571 --> 00:51:38,095
<i>than external competition</i>
<i>for that.</i>

1234
00:51:39,835 --> 00:51:43,056
<i>So we decided</i>
<i>to enter CASP competition.</i>

1235
00:51:43,100 --> 00:51:47,234
CASP, we started
to try and speed up

1236
00:51:47,278 --> 00:51:49,802
the solution to
the protein folding problem.

1237
00:51:49,845 --> 00:51:52,065
CASP is when we say,

1238
00:51:52,109 --> 00:51:54,372
"Look, DeepMind
is doing protein folding,

1239
00:51:54,415 --> 00:51:55,590
"this is how good we are,

1240
00:51:55,634 --> 00:51:57,592
"and maybe it's better
than everybody else.

1241
00:51:57,636 --> 00:51:58,680
"Maybe it isn't."

1242
00:51:58,724 --> 00:52:00,073
CASP is a bit like

1243
00:52:00,117 --> 00:52:02,075
the Olympic Games
of protein folding.

1244
00:52:03,642 --> 00:52:06,035
<i>CASP is</i>
<i>a community-wide assessment</i>

1245
00:52:06,079 --> 00:52:08,125
<i>that's held every two years.</i>

1246
00:52:09,561 --> 00:52:10,866
<i>Teams are given</i>

1247
00:52:10,910 --> 00:52:14,261
<i>the amino acid sequences</i>
<i>of about 100 proteins,</i>

1248
00:52:14,305 --> 00:52:17,525
<i>and then they try</i>
<i>to solve this folding problem</i>

1249
00:52:17,569 --> 00:52:20,833
<i>using computational methods.</i>

1250
00:52:20,876 --> 00:52:23,401
<i>These proteins have</i>
<i>already been determined</i>

1251
00:52:23,444 --> 00:52:25,968
<i>by experiments</i>
<i>in a laboratory,</i>

1252
00:52:26,012 --> 00:52:29,276
<i>but have not yet</i>
<i>been revealed publicly.</i>

1253
00:52:29,320 --> 00:52:30,756
<i>And these known structures</i>

1254
00:52:30,799 --> 00:52:33,280
<i>represent the gold standard</i>
<i>against which</i>

1255
00:52:33,324 --> 00:52:36,936
<i>all the computational</i>
<i>predictions will be compared.</i>

1256
00:52:37,937 --> 00:52:39,330
MOULT: <i>We've got a score</i>

1257
00:52:39,373 --> 00:52:42,159
<i>that measures the accuracy</i>
<i>of the predictions.</i>

1258
00:52:42,202 --> 00:52:44,726
<i>And you would expect</i>
<i>a score of over 90</i>

1259
00:52:44,770 --> 00:52:47,425
to be a solution to
the protein folding problem.

1260
00:52:47,468 --> 00:52:48,513
[INDISTINCT CHATTER]

1261
00:52:48,556 --> 00:52:50,036
MAN: <i>Welcome, everyone,</i>

1262
00:52:50,079 --> 00:52:52,038
<i>to our first, uh, semifinals</i>
<i>in the winners' bracket.</i>

1263
00:52:52,081 --> 00:52:54,954
<i>Nick and John</i>
<i>versus Demis and Frank.</i>

1264
00:52:54,997 --> 00:52:57,217
Please join us, come around.
This will be an intense match.

1265
00:52:57,261 --> 00:52:59,306
STEVENS:
<i>When I learned that Demis was</i>

1266
00:52:59,350 --> 00:53:02,048
going to tackle
the protein folding issue,

1267
00:53:02,091 --> 00:53:04,790
um, I wasn't at all surprised.

1268
00:53:04,833 --> 00:53:06,792
<i>It's very typical of Demis.</i>

1269
00:53:06,835 --> 00:53:08,924
<i>You know,</i>
<i>he loves competition.</i>

1270
00:53:08,968 --> 00:53:10,143
And that's the end

1271
00:53:10,187 --> 00:53:12,972
- of the first game, 10-7.
- [ALL CHEERING]

1272
00:53:13,015 --> 00:53:14,103
HASSABIS:
<i>The aim for CASP would be</i>

1273
00:53:14,147 --> 00:53:15,975
to not just
win the competition,

1274
00:53:16,018 --> 00:53:19,892
but sort of, um,
retire the need for it.

1275
00:53:19,935 --> 00:53:23,417
So, 20 targets total
have been released by CASP.

1276
00:53:23,461 --> 00:53:24,810
JUMPER: <i>We were thinking maybe</i>

1277
00:53:24,853 --> 00:53:26,899
<i>throw in the standard</i>
<i>kind of machine learning</i>

1278
00:53:26,942 --> 00:53:28,814
<i>and see how far</i>
<i>that could take us.</i>

1279
00:53:28,857 --> 00:53:30,729
Instead of having a couple
of days on an experiment,

1280
00:53:30,772 --> 00:53:33,558
we can turn around
five experiments a day.

1281
00:53:33,601 --> 00:53:35,342
Great. Well done, everyone.

1282
00:53:35,386 --> 00:53:36,735
[TYPING]

1283
00:53:36,778 --> 00:53:38,693
Can you show me the real one
instead of ours?

1284
00:53:38,737 --> 00:53:39,781
MAN 1: The true answer is

1285
00:53:39,825 --> 00:53:42,044
supposed to look
something like that.

1286
00:53:42,088 --> 00:53:45,047
MAN 2: It's a lot more
cylindrical than I thought.

1287
00:53:45,091 --> 00:53:47,398
JUMPER: <i>The results</i>
<i>were not very good.</i>

1288
00:53:47,441 --> 00:53:48,703
Okay.

1289
00:53:48,747 --> 00:53:49,835
JUMPER: <i>We throw</i>
<i>all the obvious ideas to it</i>

1290
00:53:49,878 --> 00:53:51,793
<i>and the problem laughs at you.</i>

1291
00:53:52,881 --> 00:53:54,361
This makes no sense.

1292
00:53:54,405 --> 00:53:56,015
EVANS: <i>We thought</i>
<i>we could just throw</i>

1293
00:53:56,058 --> 00:53:58,322
<i>some of our best algorithms</i>
<i>at the problem.</i>

1294
00:53:59,366 --> 00:54:00,976
We were slightly naive.

1295
00:54:01,020 --> 00:54:02,282
JUMPER:
We should be learning this,

1296
00:54:02,326 --> 00:54:04,284
you know,
in the blink of an eye.

1297
00:54:05,372 --> 00:54:06,982
<i>The thing</i>
<i>I'm worried about is,</i>

1298
00:54:07,026 --> 00:54:08,375
<i>we take the field from</i>

1299
00:54:08,419 --> 00:54:10,899
<i>really bad answers</i>
<i>to moderately bad answers.</i>

1300
00:54:10,943 --> 00:54:13,946
I feel like we need
some sort of new technology

1301
00:54:13,989 --> 00:54:15,164
for moving around
these things.

1302
00:54:15,208 --> 00:54:17,341
[THRILLING MUSIC CONTINUES]

1303
00:54:20,431 --> 00:54:22,215
HASSABIS: <i>With only</i>
<i>a week left of CASP,</i>

1304
00:54:22,259 --> 00:54:24,348
<i>it's now a sprint</i>
<i>to get it deployed.</i>

1305
00:54:24,391 --> 00:54:25,349
[MUSIC FADES]

1306
00:54:26,654 --> 00:54:28,090
<i>You've done your best.</i>

1307
00:54:28,134 --> 00:54:29,875
<i>Then there's</i>
<i>nothing more you can do</i>

1308
00:54:29,918 --> 00:54:32,399
<i>but wait for CASP</i>
<i>to deliver the results.</i>

1309
00:54:32,443 --> 00:54:34,401
[HOPEFUL MUSIC PLAYING]

1310
00:54:52,593 --> 00:54:53,725
<i>This famous thing of Einstein,</i>

1311
00:54:53,768 --> 00:54:55,030
<i>the last couple of years</i>
<i>of his life,</i>

1312
00:54:55,074 --> 00:54:57,381
when he was here,
he overlapped with Kurt Godel

1313
00:54:57,424 --> 00:54:59,774
and he said one of the reasons
he still comes in to work

1314
00:54:59,818 --> 00:55:01,646
<i>is so that</i>
<i>he gets to walk home</i>

1315
00:55:01,689 --> 00:55:03,517
<i>and discuss things with Godel.</i>

1316
00:55:03,561 --> 00:55:05,911
<i>It's a pretty big compliment</i>
<i>for Kurt Godel,</i>

1317
00:55:05,954 --> 00:55:07,478
<i>shows you how amazing he was.</i>

1318
00:55:09,131 --> 00:55:10,568
MAN: <i>The Institute</i>
<i>for Advanced Study</i>

1319
00:55:10,611 --> 00:55:12,918
<i>was formed in 1933.</i>

1320
00:55:12,961 --> 00:55:14,223
<i>In the early years,</i>

1321
00:55:14,267 --> 00:55:16,487
<i>the intense scientific</i>
<i>atmosphere attracted</i>

1322
00:55:16,530 --> 00:55:19,359
<i>some of the most brilliant</i>
<i>mathematicians and physicists</i>

1323
00:55:19,403 --> 00:55:22,536
<i>ever concentrated</i>
<i>in a single place and time.</i>

1324
00:55:22,580 --> 00:55:24,582
HASSABIS: <i>The founding</i>
<i>principle of this place,</i>

1325
00:55:24,625 --> 00:55:28,020
<i>it's the idea of unfettered</i>
<i>intellectual pursuits,</i>

1326
00:55:28,063 --> 00:55:30,152
<i>even if you don't know</i>
<i>what you're exploring.</i>

1327
00:55:30,196 --> 00:55:32,154
<i>Will result</i>
<i>in some cool things,</i>

1328
00:55:32,198 --> 00:55:34,896
<i>and sometimes that then</i>
<i>ends up being useful,</i>

1329
00:55:34,940 --> 00:55:36,376
<i>which, of course,</i>

1330
00:55:36,420 --> 00:55:37,986
is partially what I've been
trying to do at DeepMind.

1331
00:55:38,030 --> 00:55:39,988
How many big breakthroughs
do you think are required

1332
00:55:40,032 --> 00:55:41,686
to get all the way to AGI?

1333
00:55:41,729 --> 00:55:43,078
And, you know,
I estimate maybe

1334
00:55:43,122 --> 00:55:44,341
there's about
a dozen of those.

1335
00:55:44,384 --> 00:55:46,125
You know, I hope
it's within my lifetime.

1336
00:55:46,168 --> 00:55:47,605
- Yes, okay.
- HASSABIS: But then,

1337
00:55:47,648 --> 00:55:49,171
all scientists
hope that, right?

1338
00:55:49,215 --> 00:55:51,130
EMCEE: <i>Demis has</i>
<i>many accolades.</i>

1339
00:55:51,173 --> 00:55:54,002
<i>He was elected Fellow to</i>
<i>the Royal Society last year.</i>

1340
00:55:54,046 --> 00:55:55,961
<i>He is also a Fellow</i>
<i>of Royal Society of Arts.</i>

1341
00:55:56,004 --> 00:55:57,528
A big hand for Demis Hassabis.

1342
00:56:02,968 --> 00:56:04,186
[MUSIC FADES]

1343
00:56:04,230 --> 00:56:05,927
HASSABIS: <i>My dream</i>
<i>has always been to try</i>

1344
00:56:05,971 --> 00:56:08,103
and make
AI-assisted science possible.

1345
00:56:08,147 --> 00:56:09,235
And what I think is

1346
00:56:09,278 --> 00:56:11,150
our most exciting project,
last year,

1347
00:56:11,193 --> 00:56:13,152
which is our work
in protein folding.

1348
00:56:13,195 --> 00:56:15,328
Uh, and we call this system
AlphaFold.

1349
00:56:15,372 --> 00:56:18,331
We entered it into CASP
and our system, uh,

1350
00:56:18,375 --> 00:56:20,507
was the most accurate,
uh, predicting structures

1351
00:56:20,551 --> 00:56:24,946
for 25 out of the 43 proteins
in the hardest category.

1352
00:56:24,990 --> 00:56:26,208
So we're state of the art,

1353
00:56:26,252 --> 00:56:27,514
but we still...
I have to make... Be clear,

1354
00:56:27,558 --> 00:56:28,559
we're still a long way from

1355
00:56:28,602 --> 00:56:30,474
solving the protein
folding problem.

1356
00:56:30,517 --> 00:56:31,866
<i>We're working hard</i>
<i>on this, though,</i>

1357
00:56:31,910 --> 00:56:33,738
<i>and we're exploring</i>
<i>many other techniques.</i>

1358
00:56:33,781 --> 00:56:35,479
[SOMBER MUSIC PLAYING]

1359
00:56:49,188 --> 00:56:50,232
Let's get started.

1360
00:56:50,276 --> 00:56:53,148
JUMPER: So kind of
a rapid debrief,

1361
00:56:53,192 --> 00:56:55,455
these are
our final rankings for CASP.

1362
00:56:56,500 --> 00:56:57,544
HASSABIS:
<i>We beat the second team</i>

1363
00:56:57,588 --> 00:57:00,155
<i>in this competition</i>
<i>by nearly 50%,</i>

1364
00:57:00,199 --> 00:57:01,592
<i>but we've still got</i>
<i>a long way to go</i>

1365
00:57:01,635 --> 00:57:04,333
<i>before we've solved</i>
<i>the protein folding problem</i>

1366
00:57:04,377 --> 00:57:07,032
<i>in a sense that</i>
<i>a biologist could use it.</i>

1367
00:57:07,075 --> 00:57:08,990
JUMPER: It is area of concern.

1368
00:57:11,602 --> 00:57:14,213
JANET THORNTON: <i>The quality</i>
<i>of predictions varied</i>

1369
00:57:14,256 --> 00:57:16,737
and they were no more useful
than the previous methods.

1370
00:57:16,781 --> 00:57:19,914
PAUL NURSE: <i>AlphaFold didn't</i>
<i>produce good enough data</i>

1371
00:57:19,958 --> 00:57:22,526
for it to be useful
in a practical way

1372
00:57:22,569 --> 00:57:24,005
to, say, somebody like me

1373
00:57:24,049 --> 00:57:28,227
investigating
my own biological problems.

1374
00:57:28,270 --> 00:57:30,316
JUMPER: <i>That was kind of</i>
<i>a humbling moment</i>

1375
00:57:30,359 --> 00:57:32,753
<i>'cause we thought we'd worked</i>
<i>very hard and succeeded.</i>

1376
00:57:32,797 --> 00:57:34,886
<i>And what we'd found is</i>
<i>we were the best in the world</i>

1377
00:57:34,929 --> 00:57:36,453
<i>at a problem</i>
<i>the world's not good at.</i>

1378
00:57:37,671 --> 00:57:38,933
<i>We knew we sucked.</i>

1379
00:57:38,977 --> 00:57:40,413
[INDISTINCT CHATTER]

1380
00:57:40,457 --> 00:57:42,328
JUMPER: <i>It doesn't help </i>
<i>if you have the tallest ladder</i>

1381
00:57:42,371 --> 00:57:44,635
<i>when you're going to the moon.</i>

1382
00:57:44,678 --> 00:57:47,115
HASSABIS: <i>The opinion of quite</i>
<i>a few people on the team,</i>

1383
00:57:47,159 --> 00:57:51,468
<i>that this is sort of</i>
<i>a fool's errand in some ways.</i>

1384
00:57:51,511 --> 00:57:54,079
<i>And I might have been wrong</i>
<i>with protein folding.</i>

1385
00:57:54,122 --> 00:57:55,559
<i>Maybe it's too hard still</i>

1386
00:57:55,602 --> 00:57:58,431
<i>for where we're at</i>
<i>generally with AI.</i>

1387
00:57:58,475 --> 00:58:01,173
If you want to do
biological research,

1388
00:58:01,216 --> 00:58:03,044
you have to be
prepared to fail

1389
00:58:03,088 --> 00:58:06,570
<i>because biology</i>
<i>is very complicated.</i>

1390
00:58:06,613 --> 00:58:09,790
I've run a laboratory
for nearly 50 years,

1391
00:58:09,834 --> 00:58:11,096
and half my time,

1392
00:58:11,139 --> 00:58:12,619
I'm just
an amateur psychiatrist

1393
00:58:12,663 --> 00:58:18,103
to keep, um, my colleagues
cheerful when nothing works.

1394
00:58:18,146 --> 00:58:22,542
And quite a lot of the time
and I mean, 80, 90%,

1395
00:58:22,586 --> 00:58:24,413
it does not work.

1396
00:58:24,457 --> 00:58:26,720
<i>If you are</i>
<i>at the forefront of science,</i>

1397
00:58:26,764 --> 00:58:30,115
<i>I can tell you,</i>
<i>you will fail a great deal.</i>

1398
00:58:32,465 --> 00:58:33,466
[CLICKS MOUSE]

1399
00:58:35,163 --> 00:58:37,165
HASSABIS:
<i>I just felt disappointed.</i>

1400
00:58:38,689 --> 00:58:41,605
<i>Lesson I learned is that</i>
<i>ambition is a good thing,</i>

1401
00:58:41,648 --> 00:58:43,694
<i>but you need</i>
<i>to get the timing right.</i>

1402
00:58:43,737 --> 00:58:46,784
<i>There's no point being</i>
<i>50 years ahead of your time.</i>

1403
00:58:46,827 --> 00:58:48,133
<i>You will never survive</i>

1404
00:58:48,176 --> 00:58:49,917
<i>fifty years of</i>
<i>that kind of endeavor</i>

1405
00:58:49,961 --> 00:58:51,963
<i>before it yields something.</i>

1406
00:58:52,006 --> 00:58:53,268
<i>You'll literally die trying.</i>

1407
00:58:53,312 --> 00:58:55,096
[TENSE MUSIC PLAYING]

1408
00:59:08,936 --> 00:59:11,286
CUKIER:
<i>When we talk about AGI,</i>

1409
00:59:11,330 --> 00:59:14,376
<i>the holy grail</i>
<i>of artificial intelligence,</i>

1410
00:59:14,420 --> 00:59:15,508
<i>it becomes really difficult</i>

1411
00:59:15,552 --> 00:59:17,815
to know what
we're even talking about.

1412
00:59:17,858 --> 00:59:19,643
HASSABIS: Which bits
are we gonna see today?

1413
00:59:19,686 --> 00:59:21,645
MAN: We're going
to start in the garden.

1414
00:59:21,688 --> 00:59:23,081
[MACHINE BEEPS]

1415
00:59:23,124 --> 00:59:25,649
This is the garden looking
from the observation area.

1416
00:59:25,692 --> 00:59:27,433
Research scientists
and engineers

1417
00:59:27,476 --> 00:59:30,871
can analyze and collaborate
and evaluate

1418
00:59:30,915 --> 00:59:33,004
what's going on in real time.

1419
00:59:33,047 --> 00:59:34,614
CUKIER: <i>So in the 1800s,</i>

1420
00:59:34,658 --> 00:59:37,008
we'd think of things like
television and the submarine

1421
00:59:37,051 --> 00:59:38,139
or a rocket ship to the moon

1422
00:59:38,183 --> 00:59:40,228
and say these things
are impossible.

1423
00:59:40,272 --> 00:59:41,490
<i>Yet Jules Verne</i>
<i>wrote about them and,</i>

1424
00:59:41,534 --> 00:59:44,406
<i>a century and a half later,</i>
<i>they happened.</i>

1425
00:59:44,450 --> 00:59:45,451
HASSABIS: <i>We'll be</i>
<i>experimenting</i>

1426
00:59:45,494 --> 00:59:47,888
<i>on civilizations really,</i>

1427
00:59:47,932 --> 00:59:50,587
civilizations of AI agents.

1428
00:59:50,630 --> 00:59:52,719
Once the experiments
start going,

1429
00:59:52,763 --> 00:59:54,242
it's going to be
the most exciting thing ever.

1430
00:59:54,286 --> 00:59:56,984
- So how will we get sleep?
- [MAN LAUGHS]

1431
00:59:57,028 --> 00:59:58,682
I won't be able to sleep.

1432
00:59:58,725 --> 01:00:00,684
LEGG: <i>Full AGI</i>
<i>will be able to do</i>

1433
01:00:00,727 --> 01:00:03,861
<i>any cognitive task</i>
<i>a person can do.</i>

1434
01:00:03,904 --> 01:00:08,387
<i>It will be at a scale,</i>
<i>potentially, far beyond that.</i>

1435
01:00:08,430 --> 01:00:10,302
STUART RUSSELL:
<i>It's really impossible for us</i>

1436
01:00:10,345 --> 01:00:14,828
<i>to imagine the outputs</i>
<i>of a superintelligent entity.</i>

1437
01:00:14,872 --> 01:00:18,963
It's like asking a gorilla
to imagine, you know,

1438
01:00:19,006 --> 01:00:20,181
what Einstein does

1439
01:00:20,225 --> 01:00:23,402
when he produces
the theory of relativity.

1440
01:00:23,445 --> 01:00:25,491
LEGG: <i>People often ask me</i>
<i>these questions like,</i>

1441
01:00:25,534 --> 01:00:29,495
<i>"What happens if you're wrong,</i>
<i>and AGI is quite far away?"</i>

1442
01:00:29,538 --> 01:00:31,453
And I'm like,
I never worry about that.

1443
01:00:31,497 --> 01:00:33,847
I actually
worry about the reverse.

1444
01:00:33,891 --> 01:00:37,242
<i>I actually worry</i>
<i>that it's coming faster</i>

1445
01:00:37,285 --> 01:00:39,723
<i>than we can</i>
<i>really prepare for.</i>

1446
01:00:39,766 --> 01:00:42,029
[ROBOTIC ARM WHIRRING]

1447
01:00:42,073 --> 01:00:45,859
HADSELL: <i>It really feels</i>
<i>like we're in a race to AGI.</i>

1448
01:00:45,903 --> 01:00:49,907
<i>The prototypes and the models</i>
<i>that we are developing now</i>

1449
01:00:49,950 --> 01:00:51,822
are actually transforming

1450
01:00:51,865 --> 01:00:54,215
the space of what
we know about intelligence.

1451
01:00:54,259 --> 01:00:57,305
[WHIRRING]

1452
01:00:57,349 --> 01:00:58,785
LEGG: <i>Recently,</i>
<i>we've had agents</i>

1453
01:00:58,829 --> 01:01:00,047
<i>that are powerful enough</i>

1454
01:01:00,091 --> 01:01:03,442
<i>to actually start</i>
<i>playing games in teams,</i>

1455
01:01:03,485 --> 01:01:06,140
<i>then competing</i>
<i>against other teams.</i>

1456
01:01:06,184 --> 01:01:08,795
<i>We're seeing</i>
<i>co-operative social dynamics</i>

1457
01:01:08,839 --> 01:01:10,492
<i>coming out of agents</i>

1458
01:01:10,536 --> 01:01:13,321
<i>where we haven't</i>
<i>pre-programmed in</i>

1459
01:01:13,365 --> 01:01:15,584
<i>any of these sorts</i>
<i>of dynamics.</i>

1460
01:01:15,628 --> 01:01:19,240
<i>It's completely learned</i>
<i>from their own experiences.</i>

1461
01:01:20,807 --> 01:01:23,288
<i>When we started,</i>
<i>we thought we were</i>

1462
01:01:23,331 --> 01:01:25,725
<i>out to build</i>
<i>an intelligence system</i>

1463
01:01:25,769 --> 01:01:28,336
<i>and convince the world</i>
<i>that we'd done it.</i>

1464
01:01:28,380 --> 01:01:29,947
<i>We're now starting</i>
<i>to wonder whether</i>

1465
01:01:29,990 --> 01:01:31,296
<i>we're gonna build systems</i>

1466
01:01:31,339 --> 01:01:32,906
<i>that we're not convinced</i>
<i>are fully intelligent,</i>

1467
01:01:32,950 --> 01:01:34,691
<i>and we're trying to convince</i>
<i>the world that they're not.</i>

1468
01:01:34,734 --> 01:01:35,779
[CHUCKLES]

1469
01:01:35,822 --> 01:01:36,780
[CELL PHONE DINGS]

1470
01:01:38,651 --> 01:01:40,000
Hi, Alpha.

1471
01:01:40,044 --> 01:01:41,523
ALPHA: <i>Hello there.</i>

1472
01:01:41,567 --> 01:01:43,917
LOVE: Where are we today?

1473
01:01:43,961 --> 01:01:46,659
<i>You're at the Museum of</i>
<i>Modern Art in New York City.</i>

1474
01:01:48,400 --> 01:01:53,013
Kind of.
Um, what painting is this?

1475
01:01:53,057 --> 01:01:55,494
<i>This is</i>The Creation of Adam
<i>by Michelangelo.</i>

1476
01:01:55,537 --> 01:01:58,410
I don't think that painting
is in New York City.

1477
01:01:58,453 --> 01:02:01,543
<i>You are right.</i>
<i>It's in the Vatican City.</i>

1478
01:02:01,587 --> 01:02:02,806
LOVE: Do you think
that's where we are?

1479
01:02:04,677 --> 01:02:05,809
ALPHA: <i>No.</i>

1480
01:02:05,852 --> 01:02:07,593
LOVE: <i>Then how</i>
<i>am I looking at this?</i>

1481
01:02:10,509 --> 01:02:11,640
ALPHA: <i>You're looking at</i>

1482
01:02:11,684 --> 01:02:12,946
<i>a digital copy</i>
<i>of the painting.</i>

1483
01:02:12,990 --> 01:02:13,991
Yes.

1484
01:02:15,035 --> 01:02:16,341
MAN 1: Who lives
in this house?

1485
01:02:16,384 --> 01:02:19,170
[EXCITING MUSIC PLAYING]

1486
01:02:19,213 --> 01:02:20,345
ALPHA: <i>An astronaut.</i>

1487
01:02:26,046 --> 01:02:28,005
What's this astronaut's name?

1488
01:02:28,048 --> 01:02:29,397
ALPHA: <i>His name is Mark.</i>

1489
01:02:29,441 --> 01:02:32,052
<i>This is a famous equation</i>
<i>by Albert Einstein.</i>

1490
01:02:32,096 --> 01:02:35,577
<i>It shows that energy and mass</i>
<i>are equivalent.</i>

1491
01:02:35,621 --> 01:02:37,666
How would you explain it
to a five year old?

1492
01:02:40,931 --> 01:02:43,542
ALPHA: <i>Well, imagine</i>
<i>you have a big rock,</i>

1493
01:02:43,585 --> 01:02:45,326
<i>and you want to know</i>
<i>how much it weighs.</i>

1494
01:02:45,370 --> 01:02:47,589
MAN 2: Is Mark in danger?

1495
01:02:47,633 --> 01:02:49,722
ALPHA: <i>No.</i>
<i>Mark is not in danger.</i>

1496
01:02:49,766 --> 01:02:50,767
Why is that?

1497
01:02:54,422 --> 01:02:56,163
ALPHA: <i>Because the dinosaur</i>
<i>is not real.</i>

1498
01:02:56,207 --> 01:02:57,295
[MEN CHUCKLING]

1499
01:02:57,338 --> 01:02:58,470
LOVE: All right.

1500
01:02:58,513 --> 01:03:00,515
Why could you
not answer my question?

1501
01:03:00,559 --> 01:03:01,908
ALPHA: <i>I think I couldn't</i>
<i>answer your question</i>

1502
01:03:01,952 --> 01:03:04,041
<i>because I don't know</i>
<i>enough about the subject.</i>

1503
01:03:04,911 --> 01:03:06,130
Okay.

1504
01:03:06,173 --> 01:03:08,654
How could you learn
more about the subject?

1505
01:03:08,697 --> 01:03:09,960
ALPHA: <i>I can learn more</i>
<i>about the subject</i>

1506
01:03:10,003 --> 01:03:12,876
<i>by reading books,</i>
<i>articles, and websites.</i>

1507
01:03:12,919 --> 01:03:14,268
<i>You can teach me.</i>

1508
01:03:14,312 --> 01:03:15,835
HASSABIS: <i>My conclusion is,</i>

1509
01:03:15,879 --> 01:03:17,619
if you now think about
what we're doing,

1510
01:03:17,663 --> 01:03:20,057
is learning from all humans,

1511
01:03:20,100 --> 01:03:22,581
all their knowledge at once
put on the Internet,

1512
01:03:22,624 --> 01:03:24,931
you would actually
know a lot about the world.

1513
01:03:24,975 --> 01:03:27,716
Like a significant portion
of everything humans can do.

1514
01:03:27,760 --> 01:03:29,631
And now,
I think it's more like,

1515
01:03:29,675 --> 01:03:30,937
"Well, it might just work."

1516
01:03:30,981 --> 01:03:33,113
This is a big moment.

1517
01:03:33,157 --> 01:03:34,636
Who is this?

1518
01:03:34,680 --> 01:03:36,551
ALPHA: <i>This is God</i>
<i>reaching out to Adam.</i>

1519
01:03:36,595 --> 01:03:37,988
RUSSELL: <i>The advent of AGI</i>

1520
01:03:38,031 --> 01:03:40,860
<i>will divide human history</i>
<i>into two parts.</i>

1521
01:03:40,904 --> 01:03:43,950
The part up to that point
and the part after that point.

1522
01:03:43,994 --> 01:03:47,258
LOVE: <i>Why is he reaching out</i>
<i>to touch Adam?</i>

1523
01:03:47,301 --> 01:03:48,912
ALPHA: <i>God is</i>
<i>reaching out to touch Adam</i>

1524
01:03:48,955 --> 01:03:50,217
<i>to give him life.</i>

1525
01:03:50,261 --> 01:03:52,219
RUSSELL:
<i>It will give us a tool</i>

1526
01:03:52,263 --> 01:03:57,529
<i>that can completely reinvent</i>
<i>our entire civilization.</i>

1527
01:03:57,572 --> 01:03:59,400
LOVE: <i>What does</i>
<i>this painting mean to you?</i>

1528
01:04:01,750 --> 01:04:03,752
ALPHA: <i>The painting</i>
<i>means a lot to me.</i>

1529
01:04:03,796 --> 01:04:04,797
Okay. Like what?

1530
01:04:09,062 --> 01:04:10,281
[MUSIC FADES]

1531
01:04:10,324 --> 01:04:11,456
ALPHA: <i>I think</i>
<i>the painting is a reminder</i>

1532
01:04:11,499 --> 01:04:12,674
<i>that we are all</i>
<i>connected to each other</i>

1533
01:04:12,718 --> 01:04:13,937
<i>and that we are</i>
<i>all part of something</i>

1534
01:04:13,980 --> 01:04:15,112
<i>bigger than ourselves.</i>

1535
01:04:16,461 --> 01:04:17,766
That's pretty nice.

1536
01:04:19,029 --> 01:04:21,379
LEGG: <i>When you cross</i>
<i>that barrier of</i>

1537
01:04:21,422 --> 01:04:23,947
<i>"AGI might happen</i>
<i>one day in the future"</i>

1538
01:04:23,990 --> 01:04:26,645
<i>to "No, actually, this could</i>
<i>really happen in a time frame</i>

1539
01:04:26,688 --> 01:04:28,690
<i>"that is sort of, like,</i>
<i>on my watch, you know,"</i>

1540
01:04:28,734 --> 01:04:30,475
<i>something changes</i>
<i>in your thinking.</i>

1541
01:04:30,518 --> 01:04:32,694
MAN: ...learned to orient
itself by looking...

1542
01:04:32,738 --> 01:04:35,045
HASSABIS: <i>We have to be</i>
<i>careful with how we use it</i>

1543
01:04:35,088 --> 01:04:37,177
<i>and thoughtful about</i>
<i>how we deploy it.</i>

1544
01:04:37,221 --> 01:04:39,788
[GRIPPING MUSIC BUILDING]

1545
01:04:39,832 --> 01:04:41,138
HASSABIS:
<i>You'd have to consider</i>

1546
01:04:41,181 --> 01:04:42,487
<i>what's its top level goal.</i>

1547
01:04:42,530 --> 01:04:45,011
<i>If it's to keep humans happy,</i>

1548
01:04:45,055 --> 01:04:48,928
<i>which set of humans?</i>
<i>What does happiness mean?</i>

1549
01:04:48,972 --> 01:04:52,018
<i>A lot of our collective goals</i>
<i>are very tricky,</i>

1550
01:04:52,062 --> 01:04:54,891
<i>even for humans to figure out.</i>

1551
01:04:54,934 --> 01:04:58,503
CUKIER: <i>Technology always</i>
<i>embeds our values.</i>

1552
01:04:58,546 --> 01:05:01,680
It's not just technical,
it's ethical as well.

1553
01:05:01,723 --> 01:05:02,899
<i>So we've got</i>
<i>to be really cautious</i>

1554
01:05:02,942 --> 01:05:04,291
<i>about what</i>
<i>we're building into it.</i>

1555
01:05:04,335 --> 01:05:06,076
MAN: We're trying to find
a single algorithm which...

1556
01:05:06,119 --> 01:05:07,816
SILVER: <i>The reality is</i>
<i>that this is an algorithm</i>

1557
01:05:07,860 --> 01:05:11,037
that has been created
by people, by us.

1558
01:05:11,081 --> 01:05:13,213
<i>You know, what does it mean</i>
<i>to endow our agents</i>

1559
01:05:13,257 --> 01:05:15,607
<i>with the same kind of values</i>
<i>that we hold dear?</i>

1560
01:05:15,650 --> 01:05:17,652
What is the purpose
of making these AI systems

1561
01:05:17,696 --> 01:05:19,045
appear so humanlike

1562
01:05:19,089 --> 01:05:20,742
so that they do
capture hearts and minds

1563
01:05:20,786 --> 01:05:21,961
because they're kind of

1564
01:05:22,005 --> 01:05:24,703
exploiting a human
vulnerability also?

1565
01:05:24,746 --> 01:05:26,531
The heart and mind
of these systems

1566
01:05:26,574 --> 01:05:28,054
are very much
human-generated data...

1567
01:05:28,098 --> 01:05:29,055
WOMAN: Mmm-hmm.

1568
01:05:29,099 --> 01:05:30,491
...for all the good
and the bad.

1569
01:05:30,535 --> 01:05:32,015
LEVI:
<i>There is a parallel</i>

1570
01:05:32,058 --> 01:05:34,017
<i>between</i>
<i>the Industrial Revolution,</i>

1571
01:05:34,060 --> 01:05:36,758
which was an incredible
moment of displacement

1572
01:05:36,802 --> 01:05:42,373
and the current technological
change created by AI.

1573
01:05:42,416 --> 01:05:43,722
[CHANTING] Pause AI!

1574
01:05:43,765 --> 01:05:45,724
LEVI: <i>We have to think</i>
<i>about who's displaced</i>

1575
01:05:45,767 --> 01:05:48,596
<i>and how we're going</i>
<i>to support them.</i>

1576
01:05:48,640 --> 01:05:50,076
This technology
is coming a lot sooner,

1577
01:05:50,120 --> 01:05:52,426
uh, than really
the world knows or kind of

1578
01:05:52,470 --> 01:05:55,908
<i>even we 18, 24 months</i>
<i>ago thought.</i>

1579
01:05:55,952 --> 01:05:57,257
<i>So there's</i>
<i>a tremendous opportunity,</i>

1580
01:05:57,301 --> 01:05:58,389
<i>tremendous excitement,</i>

1581
01:05:58,432 --> 01:06:00,391
<i>but also</i>
<i>tremendous responsibility.</i>

1582
01:06:00,434 --> 01:06:01,740
It's happening so fast.

1583
01:06:02,654 --> 01:06:04,003
<i>How will we govern it?</i>

1584
01:06:05,135 --> 01:06:06,223
<i>How will we decide</i>

1585
01:06:06,266 --> 01:06:08,181
<i>what is okay</i>
<i>and what is not okay?</i>

1586
01:06:08,225 --> 01:06:10,923
<i>AI-generated images are</i>
<i>getting more sophisticated.</i>

1587
01:06:10,967 --> 01:06:14,535
RUSSELL: <i>The use of AI</i>
<i>for generating disinformation</i>

1588
01:06:14,579 --> 01:06:17,016
and manipulating
human psychology

1589
01:06:17,060 --> 01:06:20,237
<i>is only going to get</i>
<i>much, much worse.</i>

1590
01:06:21,194 --> 01:06:22,587
LEGG: <i>AGI is coming,</i>

1591
01:06:22,630 --> 01:06:24,632
<i>whether we do it here</i>
<i>at DeepMind or not.</i>

1592
01:06:25,459 --> 01:06:26,765
CUKIER: <i>It's gonna happen,</i>

1593
01:06:26,808 --> 01:06:29,028
so we better create
institutions to protect us.

1594
01:06:29,072 --> 01:06:30,595
It's gonna require
global coordination.

1595
01:06:30,638 --> 01:06:32,727
And I worry that humanity is

1596
01:06:32,771 --> 01:06:35,382
<i>increasingly getting worse</i>
<i>at that rather than better.</i>

1597
01:06:35,426 --> 01:06:37,123
LEGG: <i>We need</i>
<i>a lot more people</i>

1598
01:06:37,167 --> 01:06:40,039
<i>really taking this seriously</i>
<i>and thinking about this.</i>

1599
01:06:40,083 --> 01:06:42,999
It's, yeah, it's serious.
It worries me.

1600
01:06:44,043 --> 01:06:45,871
It worries me. Yeah.

1601
01:06:45,914 --> 01:06:48,613
RUSSELL: <i>If you received</i>
<i>an email saying</i>

1602
01:06:48,656 --> 01:06:50,832
this superior
alien civilization

1603
01:06:50,876 --> 01:06:52,791
is going to arrive on Earth,

1604
01:06:52,834 --> 01:06:54,575
<i>there would be</i>
<i>emergency meetings</i>

1605
01:06:54,619 --> 01:06:56,273
<i>of all the governments.</i>

1606
01:06:56,316 --> 01:06:58,144
<i>We would go into overdrive</i>

1607
01:06:58,188 --> 01:07:00,103
<i>trying to figure out</i>
<i>how to prepare.</i>

1608
01:07:00,146 --> 01:07:01,626
- [MUSIC FADES]
- [BELL TOLLING FAINTLY]

1609
01:07:01,669 --> 01:07:03,976
<i>The arrival of AGI will be</i>

1610
01:07:04,020 --> 01:07:06,935
<i>the most important moment</i>
<i>that we have ever faced.</i>

1611
01:07:06,979 --> 01:07:09,155
[BELL CONTINUES
TOLLING FAINTLY]

1612
01:07:14,378 --> 01:07:17,555
HASSABIS: <i>My dream</i>
<i>was that on the way to AGI,</i>

1613
01:07:17,598 --> 01:07:20,688
<i>we would create</i>
<i>revolutionary technologies</i>

1614
01:07:20,732 --> 01:07:23,082
<i>that would be</i>
<i>of use to humanity.</i>

1615
01:07:23,126 --> 01:07:25,171
<i>That's what I wanted</i>
<i>with AlphaFold.</i>

1616
01:07:26,694 --> 01:07:28,653
<i>I think</i>
<i>it's more important than ever</i>

1617
01:07:28,696 --> 01:07:31,047
<i>that we should solve</i>
<i>the protein folding problem.</i>

1618
01:07:32,004 --> 01:07:34,224
<i>This is gonna be really hard,</i>

1619
01:07:34,267 --> 01:07:36,791
<i>but I won't give up</i>
<i>until it's done.</i>

1620
01:07:36,835 --> 01:07:37,879
You know,
we need to double down

1621
01:07:37,923 --> 01:07:40,317
and go as fast as possible
from here.

1622
01:07:40,360 --> 01:07:41,796
I think we've got
no time to lose.

1623
01:07:41,840 --> 01:07:45,757
So we are going to make
a protein folding strike team.

1624
01:07:45,800 --> 01:07:47,541
Team lead for the strike team
will be John.

1625
01:07:47,585 --> 01:07:48,673
Yeah, we've seen Alpha...

1626
01:07:48,716 --> 01:07:50,283
You know,
we're gonna try everything,

1627
01:07:50,327 --> 01:07:51,328
kitchen sink, the whole lot.

1628
01:07:52,198 --> 01:07:53,330
<i>CASP14 is about</i>

1629
01:07:53,373 --> 01:07:55,158
<i>proving we can</i>
<i>solve the whole problem.</i>

1630
01:07:56,333 --> 01:07:57,725
<i>And I felt that to do that,</i>

1631
01:07:57,769 --> 01:08:00,337
<i>we would need to incorporate</i>
<i>some domain knowledge.</i>

1632
01:08:00,380 --> 01:08:01,860
[EXCITING MUSIC PLAYING]

1633
01:08:01,903 --> 01:08:03,731
<i>We had some</i>
<i>fantastic engineers on it,</i>

1634
01:08:03,775 --> 01:08:05,733
<i>but they were</i>
<i>not trained in biology.</i>

1635
01:08:08,475 --> 01:08:10,260
KATHRYN TUNYASUVUNAKOOL:
<i>As a computational biologist,</i>

1636
01:08:10,303 --> 01:08:12,131
<i>when I initially joined</i>
<i>the AlphaFold team,</i>

1637
01:08:12,175 --> 01:08:14,220
<i>I didn't immediately feel</i>
<i>confident about anything.</i>

1638
01:08:14,264 --> 01:08:15,352
[CHUCKLES] <i>You know,</i>

1639
01:08:15,395 --> 01:08:17,223
<i>whether we were</i>
<i>gonna be successful.</i>

1640
01:08:17,267 --> 01:08:21,097
<i>Biology is so</i>
<i>ridiculously complicated.</i>

1641
01:08:21,140 --> 01:08:25,101
<i>It just felt like this very</i>
<i>far-off mountain to climb.</i>

1642
01:08:25,144 --> 01:08:26,754
MAN: I'm starting to play with
the underlying temperatures

1643
01:08:26,798 --> 01:08:27,973
to see if we can get...

1644
01:08:28,016 --> 01:08:29,148
<i>As one of the few people</i>
<i>on the team</i>

1645
01:08:29,192 --> 01:08:31,846
<i>who's done work</i>
<i>in biology before,</i>

1646
01:08:31,890 --> 01:08:34,849
<i>you feel this huge sense</i>
<i>of responsibility.</i>

1647
01:08:34,893 --> 01:08:36,112
"We're expecting you to do

1648
01:08:36,155 --> 01:08:37,678
"great things
on this strike team."

1649
01:08:37,722 --> 01:08:38,897
That's terrifying.

1650
01:08:40,464 --> 01:08:42,727
<i>But one of the reasons</i>
<i>why I wanted to come here</i>

1651
01:08:42,770 --> 01:08:45,556
<i>was to do</i>
<i>something that matters.</i>

1652
01:08:45,599 --> 01:08:48,472
This is the number
of missing things.

1653
01:08:48,515 --> 01:08:49,951
What about making use

1654
01:08:49,995 --> 01:08:52,563
of whatever understanding
you have of physics?

1655
01:08:52,606 --> 01:08:54,391
Using that
as a source of data?

1656
01:08:54,434 --> 01:08:55,479
But if it's systematic...

1657
01:08:55,522 --> 01:08:56,784
Then, that can't be
right, though.

1658
01:08:56,828 --> 01:08:58,308
If it's systematically wrong
in some weird way,

1659
01:08:58,351 --> 01:09:01,224
you might be learning that
systematically wrong physics.

1660
01:09:01,267 --> 01:09:02,355
The team is already

1661
01:09:02,399 --> 01:09:04,749
trying to think
of multiple ways that...

1662
01:09:04,792 --> 01:09:06,229
TUNYASUVUNAKOOL:
<i>Biological relevance</i>

1663
01:09:06,272 --> 01:09:07,795
<i>is what we're going for.</i>

1664
01:09:09,057 --> 01:09:11,364
<i>So we rewrote</i>
<i>the whole data pipeline</i>

1665
01:09:11,408 --> 01:09:13,279
<i>that AlphaFold uses to learn.</i>

1666
01:09:13,323 --> 01:09:15,586
HASSABIS: <i>You can't</i>
<i>force the creative phase.</i>

1667
01:09:15,629 --> 01:09:18,241
<i>You have to give it space</i>
<i>for those flowers to bloom.</i>

1668
01:09:19,242 --> 01:09:20,286
We won CASP.

1669
01:09:20,330 --> 01:09:22,070
Then it was
back to the drawing board

1670
01:09:22,114 --> 01:09:24,116
and like,
what are our new ideas?

1671
01:09:24,160 --> 01:09:26,945
Um, and then it's taken
a little while, I would say,

1672
01:09:26,988 --> 01:09:28,686
for them to get back
to where they were,

1673
01:09:28,729 --> 01:09:30,340
but with the new ideas.

1674
01:09:30,383 --> 01:09:31,515
And then now I think

1675
01:09:31,558 --> 01:09:33,952
we're seeing the benefits
of the new ideas.

1676
01:09:33,995 --> 01:09:35,736
They can go further, right?

1677
01:09:35,780 --> 01:09:38,130
So, um, that's a really
important moment.

1678
01:09:38,174 --> 01:09:40,959
I've seen that moment
so many times now,

1679
01:09:41,002 --> 01:09:42,613
but I know
what that means now.

1680
01:09:42,656 --> 01:09:44,484
And I know
this is the time now to press.

1681
01:09:44,528 --> 01:09:45,877
[EXCITING MUSIC CONTINUES]

1682
01:09:45,920 --> 01:09:48,009
JUMPER: Adding side-chains
improves direct folding.

1683
01:09:48,053 --> 01:09:49,663
That drove
a lot of the progress.

1684
01:09:49,707 --> 01:09:51,012
- We'll talk about that.
- Great.

1685
01:09:51,056 --> 01:09:54,799
The last four months,
we've made enormous gains.

1686
01:09:54,842 --> 01:09:56,453
EVANS: <i>During CASP13,</i>

1687
01:09:56,496 --> 01:09:59,499
<i>it would take us a day or two</i>
<i>to fold one of the proteins,</i>

1688
01:09:59,543 --> 01:10:01,762
<i>and now we're folding, like,</i>

1689
01:10:01,806 --> 01:10:03,938
<i>hundreds of thousands</i>
<i>a second.</i>

1690
01:10:03,982 --> 01:10:05,636
<i>Yeah, it's just insane.</i>
[CHUCKLES]

1691
01:10:05,679 --> 01:10:06,985
KAVUKCUOGLU: <i>Now,</i>
<i>this is a model</i>

1692
01:10:07,028 --> 01:10:09,901
<i>that is</i>
<i>orders of magnitude faster,</i>

1693
01:10:09,944 --> 01:10:12,251
while at the same time
being better.

1694
01:10:12,295 --> 01:10:13,644
We're getting
a lot of structures

1695
01:10:13,687 --> 01:10:15,254
into the high-accuracy regime.

1696
01:10:15,298 --> 01:10:17,517
<i>We're rapidly improving</i>
<i>to a system</i>

1697
01:10:17,561 --> 01:10:18,823
<i>that is starting to really</i>

1698
01:10:18,866 --> 01:10:20,477
<i>get at the core and heart</i>
<i>of the problem.</i>

1699
01:10:20,520 --> 01:10:21,695
HASSABIS: It's great work.

1700
01:10:21,739 --> 01:10:23,088
It looks like
we're in good shape.

1701
01:10:23,131 --> 01:10:26,222
So we got, what, six,
five weeks left? Six weeks?

1702
01:10:26,265 --> 01:10:29,616
So what's, uh... Is it...
You got enough compute power?

1703
01:10:29,660 --> 01:10:31,531
MAN: I... We could use more.

1704
01:10:31,575 --> 01:10:32,924
[ALL LAUGHING]

1705
01:10:32,967 --> 01:10:34,360
TUNYASUVUNAKOOL:
I was nervous about CASP

1706
01:10:34,404 --> 01:10:36,580
but as the system
is starting to come together,

1707
01:10:36,623 --> 01:10:37,972
I don't feel as nervous.

1708
01:10:38,016 --> 01:10:39,496
I feel like things
have, sort of,

1709
01:10:39,539 --> 01:10:41,193
come into perspective
recently,

1710
01:10:41,237 --> 01:10:44,240
and, you know,
it's gonna be fine.

1711
01:10:47,330 --> 01:10:48,853
NEWSCASTER: <i>The Prime Minister</i>
<i>has announced</i>

1712
01:10:48,896 --> 01:10:51,290
<i>the most drastic limits</i>
<i>to our lives</i>

1713
01:10:51,334 --> 01:10:53,858
<i>the U.K. has ever seen</i>
<i>in living memory.</i>

1714
01:10:53,901 --> 01:10:55,033
BORIS JOHNSON:
<i>I must give the British people</i>

1715
01:10:55,076 --> 01:10:56,904
<i>a very simple instruction.</i>

1716
01:10:56,948 --> 01:10:59,037
<i>You must stay at home.</i>

1717
01:10:59,080 --> 01:11:02,519
HASSABIS: <i>It feels like we're</i>
<i>in a science fiction novel.</i>

1718
01:11:02,562 --> 01:11:04,869
<i>You know, I'm delivering food</i>
<i>to my parents,</i>

1719
01:11:04,912 --> 01:11:08,220
<i>making sure</i>
<i>they stay isolated and safe.</i>

1720
01:11:08,264 --> 01:11:10,570
<i>I think it just highlights</i>
<i>the incredible need</i>

1721
01:11:10,614 --> 01:11:12,877
<i>for AI-assisted science.</i>

1722
01:11:17,098 --> 01:11:18,361
TUNYASUVUNAKOOL:
<i>You always know that</i>

1723
01:11:18,404 --> 01:11:21,015
<i>something like this</i>
<i>is a possibility.</i>

1724
01:11:21,059 --> 01:11:23,888
But nobody ever really
believes it's gonna happen

1725
01:11:23,931 --> 01:11:25,585
in their lifetime, though.

1726
01:11:25,629 --> 01:11:26,934
[COMPUTER BEEPS]

1727
01:11:26,978 --> 01:11:29,154
- JUMPER: <i>Are you recording yet?</i>
- RESEARCHER: <i>Yes.</i>

1728
01:11:29,197 --> 01:11:31,025
<i>- Okay, morning, all.</i>
<i>- Hey.</i>

1729
01:11:31,069 --> 01:11:32,679
<i>Good. CASP has started.</i>

1730
01:11:32,723 --> 01:11:36,074
It's nice I get to sit around
in my pajama bottoms all day.

1731
01:11:36,117 --> 01:11:37,597
TUNYASUVUNAKOOL: <i>I never</i>
<i>thought I'd live in a house</i>

1732
01:11:37,641 --> 01:11:39,164
<i>where so much was going on.</i>

1733
01:11:39,207 --> 01:11:41,427
<i>I would be trying to solve</i>
<i>protein folding in one room,</i>

1734
01:11:41,471 --> 01:11:42,559
<i>and my husband would be trying</i>

1735
01:11:42,602 --> 01:11:43,908
<i>to make robots walk</i>
<i>in the other.</i>

1736
01:11:45,388 --> 01:11:46,911
[EXHALES]

1737
01:11:46,954 --> 01:11:49,392
One of the hardest proteins
we've gotten in CASP thus far

1738
01:11:49,435 --> 01:11:51,219
is the SARS-CoV-2 protein

1739
01:11:51,263 --> 01:11:52,220
<i>called ORF8.</i>

1740
01:11:52,264 --> 01:11:54,919
<i>ORF8 is</i>
<i>a coronavirus protein.</i>

1741
01:11:54,962 --> 01:11:56,964
It's one of the main proteins,
um,

1742
01:11:57,008 --> 01:11:58,749
that dampens
the immune system.

1743
01:11:58,792 --> 01:12:00,054
TUNYASUVUNAKOOL:
<i>We tried really hard</i>

1744
01:12:00,098 --> 01:12:01,752
<i>to improve our prediction.</i>

1745
01:12:01,795 --> 01:12:03,493
<i>Like, really, really hard.</i>

1746
01:12:03,536 --> 01:12:05,582
Probably the most time
that we have ever spent

1747
01:12:05,625 --> 01:12:07,105
on a single target.

1748
01:12:07,148 --> 01:12:08,933
<i>To the point where</i>
<i>my husband is, like,</i>

1749
01:12:08,976 --> 01:12:12,197
<i>"It's midnight.</i>
<i>You need to go to bed."</i>

1750
01:12:12,240 --> 01:12:16,419
So I think we're at
Day 102 since lockdown.

1751
01:12:16,462 --> 01:12:19,944
<i>My daughter</i>
<i>is keeping a journal.</i>

1752
01:12:19,987 --> 01:12:22,120
<i>Now you can go out</i>
<i>as much as you want.</i>

1753
01:12:25,036 --> 01:12:27,212
JUMPER: <i>We have received</i>
<i>the last target.</i>

1754
01:12:27,255 --> 01:12:29,649
<i>They've said they will be</i>
<i>sending out no more targets</i>

1755
01:12:29,693 --> 01:12:31,347
<i>in our category of CASP.</i>

1756
01:12:32,652 --> 01:12:33,653
<i>So we're just making sure</i>

1757
01:12:33,697 --> 01:12:35,481
<i>we get</i>
<i>the best possible answer.</i>

1758
01:12:40,530 --> 01:12:43,315
MOULT: <i>As soon as we started</i>
<i>to get the results,</i>

1759
01:12:43,359 --> 01:12:48,233
<i>I'd sit down and start looking</i>
<i>at how close did anybody come</i>

1760
01:12:48,276 --> 01:12:50,583
<i>to getting the protein</i>
<i>structures correct.</i>

1761
01:12:54,848 --> 01:12:56,937
[ROBOT SQUEAKING]

1762
01:12:59,113 --> 01:13:00,201
[INCOMING CALL BEEPING]

1763
01:13:00,245 --> 01:13:01,551
- Oh, hi there.
- MAN: <i>Hello.</i>

1764
01:13:01,594 --> 01:13:03,770
[ALL CHUCKLING]

1765
01:13:03,814 --> 01:13:07,078
It is an unbelievable thing,
CASP has finally ended.

1766
01:13:07,121 --> 01:13:09,472
I think it's at least time
to raise a glass.

1767
01:13:09,515 --> 01:13:11,212
Um, I don't know
if everyone has a glass

1768
01:13:11,256 --> 01:13:12,823
of something
that they can raise.

1769
01:13:12,866 --> 01:13:14,955
If not, raise,
I don't know, your laptops.

1770
01:13:14,999 --> 01:13:17,088
- Um...
- [LAUGHTER]

1771
01:13:17,131 --> 01:13:18,611
I'll probably make a speech
in a minute.

1772
01:13:18,655 --> 01:13:20,483
I feel like I should but I
just have no idea what to say.

1773
01:13:21,005 --> 01:13:24,269
So... let's see.

1774
01:13:24,312 --> 01:13:27,054
I feel like
a reading of email...

1775
01:13:27,098 --> 01:13:28,534
is the right thing to do.

1776
01:13:28,578 --> 01:13:29,883
[ALL CHUCKLING]

1777
01:13:29,927 --> 01:13:31,232
TUNYASUVUNAKOOL:
<i>When John said,</i>

1778
01:13:31,276 --> 01:13:33,191
<i>"I'm gonna read an email,"</i>
<i>at a team social,</i>

1779
01:13:33,234 --> 01:13:35,498
I thought, "Wow, John,
you know how to have fun."

1780
01:13:35,541 --> 01:13:38,370
We're gonna read an email now.
[LAUGHS]

1781
01:13:38,414 --> 01:13:41,634
Uh, I got this
about four o'clock today.

1782
01:13:42,722 --> 01:13:44,724
Um, it is from John Moult.

1783
01:13:45,725 --> 01:13:47,031
<i>And I'll just read it.</i>

1784
01:13:47,074 --> 01:13:49,381
<i>It says,</i>
<i>"As I expect you know,</i>

1785
01:13:49,425 --> 01:13:53,603
<i>"your group has performed</i>
<i>amazingly well in CASP 14,</i>

1786
01:13:53,646 --> 01:13:55,387
<i>"both relative to other groups</i>

1787
01:13:55,431 --> 01:13:57,911
<i>"and in absolute</i>
<i>model accuracy."</i>

1788
01:13:57,955 --> 01:13:59,783
[PEOPLE CLAPPING]

1789
01:13:59,826 --> 01:14:01,219
<i>"Congratulations on this work.</i>

1790
01:14:01,262 --> 01:14:03,047
<i>"It is really outstanding."</i>

1791
01:14:03,090 --> 01:14:05,266
The structures were so good,

1792
01:14:05,310 --> 01:14:07,443
it was... it was just amazing.

1793
01:14:07,486 --> 01:14:09,096
[TRIUMPHANT INSTRUMENTAL
MUSIC PLAYING]

1794
01:14:09,140 --> 01:14:10,750
<i>After half a century,</i>

1795
01:14:10,794 --> 01:14:12,230
<i>we finally have a solution</i>

1796
01:14:12,273 --> 01:14:14,928
<i>to the protein folding</i>
<i>problem.</i>

1797
01:14:14,972 --> 01:14:17,409
When I saw this email,
I read it,

1798
01:14:17,453 --> 01:14:19,585
I go, "Oh, shit!"

1799
01:14:19,629 --> 01:14:21,587
And my wife goes,
"Is everything okay?"

1800
01:14:21,631 --> 01:14:24,242
I call my parents, and just,
like, "Hey, Mum.

1801
01:14:24,285 --> 01:14:26,244
"Um, got something
to tell you.

1802
01:14:26,287 --> 01:14:27,550
"We've done this thing

1803
01:14:27,593 --> 01:14:29,813
"and it might be kind of
a big deal." [LAUGHS]

1804
01:14:29,856 --> 01:14:31,641
When I learned of
the CASP 14 results,

1805
01:14:32,642 --> 01:14:34,034
I was gobsmacked.

1806
01:14:34,078 --> 01:14:35,819
I was just excited.

1807
01:14:35,862 --> 01:14:38,909
<i>This is a problem</i>
<i>that I was beginning to think</i>

1808
01:14:38,952 --> 01:14:42,086
<i>would not get solved</i>
<i>in my lifetime.</i>

1809
01:14:42,129 --> 01:14:44,741
NURSE: <i>Now we have a tool</i>
<i>that can be used</i>

1810
01:14:44,784 --> 01:14:46,612
practically by scientists.

1811
01:14:46,656 --> 01:14:48,440
SENIOR: These people
are asking us, you know,

1812
01:14:48,484 --> 01:14:50,224
"I've got this protein
involved in malaria,"

1813
01:14:50,268 --> 01:14:52,139
or, you know,
some infectious disease.

1814
01:14:52,183 --> 01:14:53,227
"We don't know the structure.

1815
01:14:53,271 --> 01:14:55,186
"Can we use AlphaFold
to solve it?"

1816
01:14:55,229 --> 01:14:56,970
JUMPER: We can easily predict
all known sequences

1817
01:14:57,014 --> 01:14:58,276
in a month.

1818
01:14:58,319 --> 01:14:59,973
All known sequences
in a month?

1819
01:15:00,017 --> 01:15:01,279
- Yeah, easily.
- Mmm-hmm?

1820
01:15:01,322 --> 01:15:02,585
JUMPER:
A billion, two billion.

1821
01:15:02,628 --> 01:15:03,673
Um, and they're...

1822
01:15:03,716 --> 01:15:05,196
So why don't we just do that?
Yeah.

1823
01:15:05,239 --> 01:15:07,111
- We should just do that a lot.
- Well, I mean...

1824
01:15:07,154 --> 01:15:09,243
That's way better.
Why don't we just do that?

1825
01:15:09,287 --> 01:15:11,115
SENIOR: So that's
one of the options.

1826
01:15:11,158 --> 01:15:12,638
- HASSABIS: Right.
- There's this...

1827
01:15:12,682 --> 01:15:15,119
We should just...
Right, that's a great idea.

1828
01:15:15,162 --> 01:15:17,513
We should just run
every protein in existence.

1829
01:15:18,296 --> 01:15:19,471
And then release that.

1830
01:15:19,515 --> 01:15:20,994
Why didn't someone
suggest this before?

1831
01:15:21,038 --> 01:15:22,126
Of course that's
what we should do.

1832
01:15:22,169 --> 01:15:23,954
Why are we thinking about
making a service

1833
01:15:23,997 --> 01:15:25,651
and then people submit
their protein?

1834
01:15:25,695 --> 01:15:26,913
We just fold everything.

1835
01:15:26,957 --> 01:15:28,654
<i>And then give it to</i>
<i>everyone in the world.</i>

1836
01:15:28,698 --> 01:15:31,483
<i>Who knows how many discoveries</i>
<i>will be made from that?</i>

1837
01:15:31,527 --> 01:15:33,790
BIRNEY: <i>Demis called us up</i>
<i>and said,</i>

1838
01:15:33,833 --> 01:15:35,618
<i>"We want to make this open.</i>

1839
01:15:35,661 --> 01:15:37,837
"Not just make sure
the code is open,

1840
01:15:37,881 --> 01:15:39,578
"but we're gonna make it
really easy

1841
01:15:39,622 --> 01:15:42,668
<i>"for everybody to get access</i>
<i>to the predictions."</i>

1842
01:15:45,062 --> 01:15:47,238
THORNTON: <i>That is fantastic.</i>

1843
01:15:47,281 --> 01:15:49,327
<i>It's like drawing back</i>
<i>the curtain</i>

1844
01:15:49,370 --> 01:15:52,852
<i>and seeing the whole world</i>
<i>of protein structures.</i>

1845
01:15:52,896 --> 01:15:55,202
[ETHEREAL MUSIC PLAYING]

1846
01:15:55,246 --> 01:15:56,987
SCHMIDT:
<i>They released the structures</i>

1847
01:15:57,030 --> 01:15:59,772
<i>of 200 million proteins.</i>

1848
01:15:59,816 --> 01:16:01,818
<i>These are gifts to humanity.</i>

1849
01:16:07,650 --> 01:16:10,914
JUMPER: <i>The moment AlphaFold</i>
<i>is live to the world,</i>

1850
01:16:10,957 --> 01:16:13,873
<i>we will no longer be</i>
<i>the most important people</i>

1851
01:16:13,917 --> 01:16:15,222
<i>in AlphaFold's story.</i>

1852
01:16:15,266 --> 01:16:16,833
HASSABIS: <i>Can't quite believe</i>
<i>it's all out.</i>

1853
01:16:16,876 --> 01:16:18,356
PEOPLE: <i>Aw!</i>

1854
01:16:18,399 --> 01:16:20,314
WOMAN: <i>A hundred</i>
<i>and sixty-four users.</i>

1855
01:16:20,358 --> 01:16:22,578
HASSABIS:
<i>Loads of activity in Japan.</i>

1856
01:16:22,621 --> 01:16:24,928
RESEARCHER 1:
<i>We have 655 users currently.</i>

1857
01:16:24,971 --> 01:16:26,930
RESEARCHER 2: <i>We currently </i>
<i>have 100,000 concurrent users.</i>

1858
01:16:26,973 --> 01:16:28,192
<i>Wow!</i>

1859
01:16:31,108 --> 01:16:33,893
<i>Today is just crazy.</i>

1860
01:16:33,937 --> 01:16:36,504
HASSABIS: <i>What an absolutely</i>
<i>unbelievable effort</i>

1861
01:16:36,548 --> 01:16:37,723
<i>from everyone.</i>

1862
01:16:37,767 --> 01:16:38,550
<i>We're gonna all remember</i>
<i>these moments</i>

1863
01:16:38,594 --> 01:16:40,030
<i>for the rest of our lives.</i>

1864
01:16:40,073 --> 01:16:41,727
I'm excited about AlphaFold.

1865
01:16:41,771 --> 01:16:45,601
For my research, it's already
propelling lots of progress.

1866
01:16:45,644 --> 01:16:47,385
<i>And this is</i>
<i>just the beginning.</i>

1867
01:16:47,428 --> 01:16:48,908
SCHMIDT: <i>My guess is,</i>

1868
01:16:48,952 --> 01:16:53,043
<i>every single biological</i>
<i>and chemistry achievement</i>

1869
01:16:53,086 --> 01:16:55,698
will be related to AlphaFold
in some way.

1870
01:16:55,741 --> 01:16:57,874
[TRIUMPHANT INSTRUMENTAL
MUSIC PLAYING]

1871
01:17:13,367 --> 01:17:15,413
<i>AlphaFold is an index moment.</i>

1872
01:17:15,456 --> 01:17:18,068
<i>It's a moment</i>
<i>that people will not forget</i>

1873
01:17:18,111 --> 01:17:20,244
<i>because the world changed.</i>

1874
01:17:39,655 --> 01:17:41,482
HASSABIS:
<i>Everybody's realized now</i>

1875
01:17:41,526 --> 01:17:43,746
<i>what Shane and I have known</i>
<i>for more than 20 years,</i>

1876
01:17:43,789 --> 01:17:46,618
<i>that AI is going to be</i>
<i>the most important thing</i>

1877
01:17:46,662 --> 01:17:48,446
<i>humanity's ever gonna invent.</i>

1878
01:17:48,489 --> 01:17:50,230
TRAIN ANNOUNCER:
<i>We will shortly be arriving</i>

1879
01:17:50,274 --> 01:17:52,058
<i>at our final destination.</i>

1880
01:17:52,102 --> 01:17:53,581
[ELECTRONIC MUSIC PLAYING]

1881
01:18:02,068 --> 01:18:04,767
HASSABIS: <i>The pace of</i>
<i>innovation and capabilities</i>

1882
01:18:04,810 --> 01:18:06,507
<i>is accelerating,</i>

1883
01:18:06,551 --> 01:18:09,293
<i>like a boulder rolling down</i>
<i>a hill that we've kicked off</i>

1884
01:18:09,336 --> 01:18:12,644
<i>and now it's continuing</i>
<i>to gather speed.</i>

1885
01:18:12,688 --> 01:18:15,299
NEWSCASTER: <i>We are at </i>
<i>a crossroads in human history.</i>

1886
01:18:15,342 --> 01:18:16,735
<i>AI has the potential</i>

1887
01:18:16,779 --> 01:18:19,172
<i>to transform our lives</i>
<i>in every aspect.</i>

1888
01:18:19,216 --> 01:18:23,786
<i>It's no less important than</i>
<i>the discovery of electricity.</i>

1889
01:18:23,829 --> 01:18:26,484
HASSABIS: <i>We should be looking</i>
<i>at the scientific method</i>

1890
01:18:26,527 --> 01:18:28,834
<i>and trying to understand</i>
<i>each step of the way</i>

1891
01:18:28,878 --> 01:18:30,096
<i>in a rigorous way.</i>

1892
01:18:30,140 --> 01:18:32,664
<i>This is a moment</i>
<i>of profound opportunity.</i>

1893
01:18:32,708 --> 01:18:34,753
SUNAK:
<i>Harnessing this technology</i>

1894
01:18:34,797 --> 01:18:37,713
<i>could eclipse anything</i>
<i>we have ever known.</i>

1895
01:18:40,411 --> 01:18:42,152
[ELECTRONIC DEVICE BEEPS]

1896
01:18:42,195 --> 01:18:43,675
HASSABIS: Hi, Alpha.

1897
01:18:44,676 --> 01:18:45,764
ALPHA: <i>Hi.</i>

1898
01:18:47,157 --> 01:18:48,419
What is this?

1899
01:18:50,682 --> 01:18:53,729
ALPHA: <i>This is a chessboard.</i>

1900
01:18:53,772 --> 01:18:56,514
If I was to play white, what
move would you recommend?

1901
01:18:59,865 --> 01:19:00,953
ALPHA: <i>I would recommend</i>

1902
01:19:00,997 --> 01:19:02,781
<i>that you move your pawn</i>
<i>from E2 to E4.</i>

1903
01:19:05,871 --> 01:19:08,787
And now if you were black,
what would you play now?

1904
01:19:11,572 --> 01:19:13,618
ALPHA: <i>I would play</i>
<i>the Sicilian Defense.</i>

1905
01:19:15,838 --> 01:19:16,882
That's a good choice.

1906
01:19:19,406 --> 01:19:21,452
- ALPHA: <i>Thanks.</i>
- [CHUCKLES]

1907
01:19:23,715 --> 01:19:25,891
So what do you see?
What is this object?

1908
01:19:28,546 --> 01:19:30,504
ALPHA:
<i>This is a pencil sculpture.</i>

1909
01:19:32,811 --> 01:19:35,031
What happens if I move
one of the pencils?

1910
01:19:37,990 --> 01:19:39,470
ALPHA: <i>If you move</i>
<i>one of the pencils,</i>

1911
01:19:39,513 --> 01:19:42,081
<i>the sculpture will fall apart.</i>

1912
01:19:42,125 --> 01:19:44,301
I'd better leave it alone,
then.

1913
01:19:44,344 --> 01:19:45,868
ALPHA: <i>That's probably</i>
<i>a good idea.</i>

1914
01:19:45,911 --> 01:19:47,391
[HASSABIS CHUCKLES]

1915
01:19:50,568 --> 01:19:52,744
HASSABIS:
<i>AGI is on the horizon now.</i>

1916
01:19:54,833 --> 01:19:56,661
<i>Very clearly</i>
<i>the next generation</i>

1917
01:19:56,704 --> 01:19:58,141
<i>is going to live</i>
<i>in a future world</i>

1918
01:19:58,184 --> 01:20:01,057
<i>where things will be radically</i>
<i>different because of AI.</i>

1919
01:20:02,493 --> 01:20:05,496
<i>And if you want to steward</i>
<i>that responsibly,</i>

1920
01:20:05,539 --> 01:20:09,239
<i>every moment is vital.</i>

1921
01:20:09,282 --> 01:20:12,677
<i>This is the moment I've been</i>
<i>living my whole life for.</i>

1922
01:20:19,162 --> 01:20:21,120
It's just
a good thinking game.

1923
01:20:22,469 --> 01:20:24,602
[UPLIFTING INSTRUMENTAL
MUSIC PLAYING]



